Estimated reading timeApproximately 9 minutes, total 3273 words. Introduction Last week, we shared a commentary by Professor Zhang Jian and Dr. Jin Yizi from Fudan University Shanghai Cancer Center on the article “The Incidence of Oral Mucositis and Oral Ulcerative Mucosal Toxicities in Cancer Treatment” published in CA Journal. Did you find it insufficient? Starting … Read more
Click the “Chinese Practical Surgery Journal” above to subscribe! [Cite this article] National Health Commission of the People’s Republic of China. Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition) [J]. Chinese Practical Surgery Journal, 2022, 42(3): 241-273. Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition) National Health … Read more
Source: New Youth Medical Alliance Author: Big Sword Brother Tells Stories 01Small Characters, Big Roles Analyzing the subfields of medical devices is one of the directions for this year’s public WeChat account of the New Youth Medical Alliance. Following in vitro diagnosis and medical imaging (“Breaking Through in the Context of Domestic Production: The Path … Read more
Since the concept of ADC was proposed in 1900, it has existed as a new type of cancer treatment method. Although its development has faced many challenges over the past century, top scientists in the relevant fields around the world have been conducting years of experiments and iterations to improve safety, reduce off-target effects, and … Read more
△ A grand contribution, 1 main forum, 5 sub-forums, 9 thematic forums, hundreds of industry leaders, many renowned clinical PIs and dozens of CMOs gathered, a thousand-person conference awaits you! ▼ Antibody-drug conjugates (ADCs) are currently developing rapidly, utilizing antibodies to selectively deliver cytotoxic drugs to tumor sites. As of May 2021, the U.S. Food … Read more
To build a global highland for the future ADC/RDC industry, Chengdu Medical City plans to hold the first Future XDC New Drug Conference from April 18 to 19, 2024! The conference, themed “Co-creating the Future of the Conjugated Drug Industry,” is organized by Tongxi Yi Planning, featuring a main forum and nine thematic forums. Experts … Read more
Click below to follow and never miss cancer knowledge~ Author: Guo Lin When it comes to cancer treatment, chemotherapy, surgery, and radiotherapy are the most familiar traditional methods. However, with the advancement of anti-cancer technology, a new type of “smart” anti-cancer drug that combines the advantages of chemotherapy and targeted drugs—Antibody Drug Conjugates (ADC)—has gradually … Read more
Let’s take a moment to focus on the recent hot topic of Antibody–Drug Conjugates and systematically learn about the review published in Cancers: Antibody–Drug Conjugates for the Treatment of Breast Cancer. Abstract Currently, aside from endocrine therapy and targeted drugs, the common treatment method for metastatic breast cancer (BC) is chemotherapy. However, the lack of … Read more
1. Overview Antibody-drug conjugates (ADCs) rejuvenate the concept of targeted chemotherapy by coupling cytotoxic payloads to antibodies. The first stage of the complex intracellular toxin delivery process of ADCs is endocytosis. Analyzing the endocytic action of target receptors and ADCs can greatly advance preclinical research, clinical translation, and patient treatment outcomes. The in vitro efficacy … Read more
Author｜Wenxin As of now, regarding thetoxicity of ADCs in solid tumors and preventive measures, the following is known: ① The indications for ADCs are rapidly expanding, gradually shifting from late-stage to early-stage, and from single therapy to combination strategies. ② The toxicity characteristics of most ADCs are similar to the cytotoxicity of their payloads. ③ … Read more