Immunohistochemistry

Pathological Diagnosis, Staging, and Classification of Liver Cancer

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Pathological Diagnosis, Staging, and Classification of Liver Cancer

Liver cancer is currently the 4th most common malignant tumor in China and the 2nd leading cause of cancer-related death. Liver cancer mainly includes three different pathological types: hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and combined hepatocellular carcinoma-cholangiocarcinoma (cHCC-CCA). These types differ significantly in terms of pathogenesis, biological behavior, histopathology, treatment methods, and prognosis, with … Read more

Immunohistochemistry Guide: Significance of 57 Common Clinical Indicators

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Micro Diagnosis Network WeChat ID: ivdcom New Media in Laboratory Medicine (www.weivd.com） What Is the Difference Between IHC and ICC? The principle of immunohistochemistry (IHC) has been known since the 1930s, but the first IHC research results were not officially published until 1942. This is regarded as a milestone in immunofluorescence technology. Albert Coons from … Read more

Summary of Immunohistochemical Markers for Liver Cancer

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Summary of Immunohistochemical Markers for Liver Cancer

In 2020, over 410,000 new cases of liver cancer were reported in China, with more than 390,000 deaths due to liver cancer, bringing the death toll close to the number of new cases. This means that for every 11 newly diagnosed cancer patients, 1 has liver cancer, and almost 1 in 8 patients who die … Read more

Principles and Color Matching of Secondary Antibody Selection

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Principles and Color Matching of Secondary Antibody Selection

Antibody Antibodies have been analyzed by X-ray crystallography, revealing that Ig consists of four polypeptide chains connected by varying numbers of interchain disulfide bonds. Ig can form a “Y” shaped structure, known as an Ig monomer, which is the basic unit of antibodies. Basic Unit of Antibody The primary antibody specifically recognizes and binds to … Read more

Immunohistochemistry: Significance of 57 Common Clinical Indicators

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Immunohistochemistry: Significance of 57 Common Clinical Indicators

What is the difference between IHC and ICC?In the 1930s, the principles of immunohistochemistry (IHC) were already known, but it wasn’t until 1942 that the first IHC research results were officially published. This is regarded as a milestone in immunofluorescence technology. Albert Coons from Harvard Medical School published an article in the Journal of Immunology, … Read more

In-Depth Analysis of the IVD Pathological Diagnosis Industry Chain

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In-Depth Analysis of the IVD Pathological Diagnosis Industry Chain

Source: New Youth Medical Alliance Author: Big Sword Brother Tells Stories 01Small Characters, Big Roles Analyzing the subfields of medical devices is one of the directions for this year’s public WeChat account of the New Youth Medical Alliance. Following in vitro diagnosis and medical imaging (“Breaking Through in the Context of Domestic Production: The Path … Read more

Distinguishing Between IHC, ICC, and IF

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Distinguishing Between IHC, ICC, and IF

Immunohistochemistry, Immunocytochemistry, and Immunofluorescence are three commonly used applications in biology, with their English names being Immunohistochemistry (IHC), Immunocytochemistry (ICC), and Immunofluorescence (IF). Root meanings: Immuno- refers to immune techniques (for example, the binding of antibodies and antigens). Histo- refers to tissues (cells and their surrounding extracellular matrix). Cyto- refers to cells (excluding the extracellular … Read more

Differences Between IHC and ICC: 57 Clinical Immunohistochemistry Indicators

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Differences Between IHC and ICC: 57 Clinical Immunohistochemistry Indicators

What Are the Differences Between IHC and ICC? In the 1930s, the principle of Immunohistochemistry (IHC) was already known, but it wasn’t until 1942 that the first IHC research results were officially published, marking a milestone in immunofluorescence technology. Albert Coons from Harvard Medical School published an article in the Journal of Immunology, using FITC-labeled … Read more

Understanding IF, ICC, and IHC Techniques

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Understanding IF, ICC, and IHC Techniques

Technical Terms are often confused with Immunofluorescence, Immunocytochemistry, and Immunohistochemistry. These three terms are often used interchangeably, which can lead to confusion when purchasing antibodies for microscopic experiments. Immunofluorescence (IF) Immunofluorescence (IF) refers to the detection method used (i.e., using fluorescent dyes to visualize the target of interest), regardless of the type of sample used. … Read more

Understanding IHC, ICC, and IF: Clearing Up Common Confusions

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Understanding IHC, ICC, and IF: Clearing Up Common Confusions

Immunohistochemistry、Immunocytochemistry and Immunofluorescence are three commonly used applications. Do you often feel confused about these three applications? They indeed have many similarities. Let’s clarify their differences. IF (Immunofluorescence) / IHC (Immunohistochemistry) / ICC (Immunocytochemistry) are three applications, and one part that everyone will definitely not confuse is “Immuno”, because all three applications involve the use … Read more