breast cancer

Literature Sharing | S. multivorum in Tumors Promotes Progression of Triple-Negative Breast Cancer by Suppressing Tumor Immuno-surveillance

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Literature Sharing | S. multivorum in Tumors Promotes Progression of Triple-Negative Breast Cancer by Suppressing Tumor Immuno-surveillance

Click the blue text to follow us Literature Review This week’s shared literature is a study published on January 8, 2025, by Zhikai Mai from the Foshan Maternal and Child Health Hospital in the journal Molecular Cancer (IF: 27.7; Q1 in Zone 1), titled “Intra-tumoral sphingobacterium multivorum promotes triple-negative breast cancer progression by suppressing tumor … Read more

Understanding Targeted Therapies for HER2-Positive Advanced Breast Cancer: Focus on Five Categories

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The human epidermal growth factor receptor 2 (HER2) is a known important molecular target in breast cancer. As one of the proto-oncogenes, HER2 is often associated with aggressiveness, recurrence, metastasis, and poor prognosis. The clinical application of the anti-HER2 drug trastuzumab has significantly improved the diagnosis and treatment patterns and prognosis of HER2-positive breast cancer, … Read more

Clinical Research Confirms DS-8201 Effectively Treats Brain Metastases from Breast Cancer

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Clinical Research Confirms DS-8201 Effectively Treats Brain Metastases from Breast Cancer

Written by Wang Cong Edited by Wang Duoyu Formatted by Shui Chengwen Breast cancer has the highest incidence rate among malignant tumors in women, thus it is referred to as the “pink killer.” According to the global cancer burden data released by the International Agency for Research on Cancer (IARC) in 2020, breast cancer has … Read more

What Are ADC Drugs? Which Breast Cancer Patients Can Receive ADC Treatment?

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What Are ADC Drugs? Which Breast Cancer Patients Can Receive ADC Treatment?

Breast cancer, regarded as the “killer of beauty,” is a malignant tumor that severely threatens women’s health, with an increasing incidence year by year. Antibody-drug conjugates (ADC), as a new type of therapeutic drug, have become a hot research topic in the field of breast cancer due to their advantages of “high efficacy and low … Read more

How to Use ADCs? Managing Adverse Reactions? Expert Recommendations

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How to Use ADCs? Managing Adverse Reactions? Expert Recommendations

*For reference by medical professionals only Antibody-drug conjugates (ADCs) have become a new hotspot in the field of anti-tumor therapy, with explorations in the treatment of breast cancer, lung cancer, gastric cancer, colorectal cancer, and other types of cancer. With the approval and clinical entry of drugs such as Trastuzumab Deruxtecan, Ado-trastuzumab emtansine, and Enfortumab … Read more

Cold Exposure Therapy Enhances Breast Cancer Treatment

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Cold Exposure Therapy Enhances Breast Cancer Treatment

iNature Cold exposure therapy (CE) is a low-cost, non-invasive treatment for malignant tumors. When the body is exposed to a cold environment, it activates the thermogenic metabolism of brown adipose tissue (BAT), quickly inducing tumor starvation and inhibiting tumor growth. The microenvironmental changes caused by CE can further complement conventional treatments (such as radiotherapy and … Read more

Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound

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Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound

Source Qian Zhang, Jiaxing Wang, Yanjun Ding, et al. Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound. Chinese Journal of Medical Imaging, 2020, 28(12): 907-911+917 Abstract Objective To explore the ability of the phase-change nanoparticles (Ce6@PFP/PLGA NPs) loaded with the sonosensitizer Chlorin e6 (Ce6) and perfluoropentane (PFP) combined with low-intensity … Read more

ADC Case Study: Overcoming Metastatic Breast Cancer

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ADC Case Study: Overcoming Metastatic Breast Cancer

Expert Commentary Professor Yuan Zhongyu Department of Internal Medicine, Sun Yat-sen University Cancer Prevention and Treatment Center Chief Physician, MD, Doctoral Supervisor Engaged in clinical and research work on breast cancer for many years, has presided over and participated in over 20 clinical studies, involved in several research projects such as the National 863 Program … Read more

Case Sharing of ADC: A HER2-Positive Breast Cancer Case

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Case Sharing of ADC: A HER2-Positive Breast Cancer Case

Expert Commentary Professor Feng Jifeng Chief Physician, Professor, Doctoral Supervisor Secretary of the Party Committee, Jiangsu Provincial Cancer Hospital/Nanjing Medical University Affiliated Cancer Hospital Member of the Expert Committee on Rational Drug Use, National Health Commission Council Member of the Chinese Medical Association, Member of the Internal Medicine Group of the Oncology Branch Vice President … Read more

ADC Drug Combination: How to Achieve 1+1>2

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ADC Drug Combination: How to Achieve 1+1>2

Antibody-drug conjugates (ADC) are a novel type of medication that couples monoclonal antibodies, which specifically recognize cancer cell surface antigens, with cytotoxic chemotherapy drugs through specific linkers, exerting a significant tumor-killing effect. Currently, 15 ADC drugs, represented by trastuzumab emtansine (T-DM1) and trastuzumab deruxtecan (T-DXd, DS-8201), have been approved globally, significantly changing the treatment landscape … Read more