Metabolic Biomarkers

JTO Authority Review: Efficacy and Safety of Neoadjuvant Targeted Therapy for Resectable NSCLC

by
JTO Authority Review: Efficacy and Safety of Neoadjuvant Targeted Therapy for Resectable NSCLC

The standard treatment (SoC) for surgically resectable early-stage (I-IIIB) NSCLC patients is surgery combined with (new) adjuvant systemic therapy for patients with stage II to IIIB and certain stage IB patients, with chemotherapy and radiotherapy used in select cases (for stage III disease with mediastinal lymph node metastasis). Despite these treatments, metastatic recurrence is common … Read more

8 Clinical Significances of Elevated C-Reactive Protein Beyond Bacterial Infection

by
8 Clinical Significances of Elevated C-Reactive Protein Beyond Bacterial Infection

C-reactive protein (CRP) is an acute-phase response protein induced by interleukin 6 (IL-6) produced in liver cells, with normal reference value < 5 mg/L. The advancement of testing technology has improved the sensitivity and accuracy of CRP detection. Existing testing instruments can detect extremely low concentrations of CRP in serum samples, known as high-sensitivity C-reactive … Read more

Biomarkers and Targeted Therapy for Intrahepatic Cholangiocarcinoma

by
Biomarkers and Targeted Therapy for Intrahepatic Cholangiocarcinoma

Introduction Although rare, intrahepatic cholangiocarcinoma (ICC) is the second most common primary malignant tumor of the liver, with approximately 8,000 cases diagnosed annually in the United States, accounting for only 3% of gastrointestinal malignancies diagnosed worldwide each year. The incidence of ICC has increased over the past few decades, with some studies indicating a 14% … Read more

The Diagnostic Value of Biomarkers in Sepsis-Related Myocardial Dysfunction

by

Follow us for more exciting content SIC Sepsis-Induced Cardiomyopathy (SIC) is an acute heart dysfunction that occurs in sepsis patients and is not related to ischemic injury, but lacks a unified diagnostic standard. Some biological markers can reflect the degree of heart damage and have certain auxiliary value for the early diagnosis of sepsis-induced cardiomyopathy. … Read more

Literature Sharing | J. Am. Chem. Soc. | Alkynyl Platinum Complex Self-Assembly for Sialic Acid Detection and Differentiation of Cancer Cells from Normal Cells

by
Literature Sharing | J. Am. Chem. Soc. | Alkynyl Platinum Complex Self-Assembly for Sialic Acid Detection and Differentiation of Cancer Cells from Normal Cells

The team led by Ren Yonghua at the University of Hong Kong designed and synthesized a series of platinum(II) complexes containing histidine moieties or positively charged groups to explore the specific binding and sensing capabilities of platinum(II) complexes with analytes. These complexes are used to visualize changes in sialic acid within cells, distinguishing between normal … Read more

2025 ASCO Review: ADC Continues to Lead Cancer Treatment, Innovative Target Efficacy Begins to Show, Domestic Technology Platforms Achieve Multidimensional Breakthroughs

by
2025 ASCO Review: ADC Continues to Lead Cancer Treatment, Innovative Target Efficacy Begins to Show, Domestic Technology Platforms Achieve Multidimensional Breakthroughs

The 2025 American Society of Clinical Oncology (ASCO) Annual Meeting grandly opened in Chicago on May 31, lasting for 4 days, with the theme “Driving Knowledge to Action: Building a Better Future,” focusing on the latest research progress and innovative translational achievements in the global cancer treatment field. ADC drugs remain a hot area of … Read more

Nano Energy Develops Self-Powered Friction Sensor for Wearable Monitoring

by
Nano Energy Develops Self-Powered Friction Sensor for Wearable Monitoring

This article is reproduced from the WeChat public account “Tianjin Medical University” Fang Zhongze Professor at Tianjin Medical University, PhD supervisor, Vice Dean of the School of Public Health, Executive Deputy Director of the National Preventive Medicine Experimental Teaching Center, Director of the Department of Health Toxicology and Health Inspection and Quarantine, and Deputy Director … Read more