Inflammation

Mechanisms and Prevention of Acute Pancreatitis Complicating Liver Failure

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Mechanisms and Prevention of Acute Pancreatitis Complicating Liver Failure

Liver failure is a severe destruction of hepatocytes triggered by various pathological factors, leading to significant liver dysfunction. In clinical practice, it is often characterized by ascites, jaundice, hepatorenal syndrome, and infections, commonly associated with systemic inflammatory response syndrome. Its onset is rapid, the progression is swift, and it has many complications, making it extremely … Read more

Detailed Explanation of C-Reactive Protein

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Detailed Explanation of C-Reactive Protein

CRP is an acute phase protein synthesized by liver cells in response to inflammatory stimuli such as microbial invasion or tissue damage. The acute phase response includes changes in the concentration of certain serum proteins during infection, inflammation, and trauma. These proteins, in addition to CRP, include serum amyloid A, fibrinogen, haptoglobin, α1-acid glycoprotein, ceruloplasmin, … Read more

How Inflammation Promotes Atherosclerosis: The Key Steps

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How Inflammation Promotes Atherosclerosis: The Key Steps

▎Content Team of WuXi AppTec Edited Lipid accumulation and hypertension are considered major risk factors for atherosclerotic cardiovascular disease (ASCVD). Cholesterol-lowering and antihypertensive medications are expected to effectively prevent and eliminate ASCVD. However, intervention strategies based on hypercholesterolemia and hypertension have failed to produce ideal results due to the exclusion of chronic vascular inflammation. The … Read more