C-Reactive Protein (CRP) is an acute-phase protein synthesized by hepatocytes, with very low expression levels in healthy human serum. Its expression significantly increases during trauma, infection, etc., mainly regulated by inflammatory factors such as tumor necrosis factor and interleukins. It is synthesized by the liver and is a non-specific acute-phase response protein. The expression of … Read more
C-reactive protein (CRP) is an acute-phase response protein induced by interleukin 6 (IL-6) produced in liver cells, with normal reference value < 5 mg/L. The advancement of testing technology has improved the sensitivity and accuracy of CRP detection. Existing testing instruments can detect extremely low concentrations of CRP in serum samples, known as high-sensitivity C-reactive … Read more
Are CRP and hsCRP testing the same thing? Some say they are the same, while others disagree. Many clinical doctors in hospitals also tend to confuse them. Why do we have two testing ranges for one substance? Today, I will briefly share with you these two familiar yet unfamiliar testing items. First, CRP and hsCRP … Read more
High-Sensitivity C-Reactive Protein Hello everyone, today we continue to discuss the indicator of high-sensitivity C-reactive protein. What should we do when the high-sensitivity C-reactive protein is elevated?High-sensitivity C-reactive protein, as a sensitive inflammatory marker, accurately reflects the stability of vascular plaques and is recognized in clinical settings as one of the strongest predictors of cardiovascular … Read more
First People’s Hospital of Zhoukou City Medical Laboratory Department Zhao Kunpeng When children have a fever or a cold, doctors often recommend blood tests, mainly checking the blood routine and C-reactive protein. Many parents often ask: Doctor, what is the difference between C-Reactive Protein and High-Sensitivity C-Reactive Protein? First, let’s understand their specific definitions C-Reactive … Read more
Click the blue text above to follow us C-Reactive Protein (CRP) is an acute-phase protein that sharply rises in plasma when the body is infected or when tissue is damaged. It plays a role in activating complement and enhancing the phagocytosis of macrophages.As an inflammatory marker, CRP has been widely used in clinical practice. Common … Read more
What does C-Reactive Protein look like? C-Reactive Protein (CRP) appears as a symmetrical, ring-shaped pentamer, with a molecular metabolic half-life of only 5-7 hours. ▼ How is C-Reactive Protein synthesized in the body? C-Reactive Protein is synthesized in response to inflammatory lymphokines (interleukin-6, interleukin-1, tumor necrosis factor TNF) that stimulate the liver and epithelial cells. … Read more
C-Reactive Protein C-Reactive Protein (CRP), discovered by Tillett and Francis in 1930, is a pentameric protein synthesized by the liver. During acute inflammation or infection, CRP levels rise significantly, primarily induced by interleukin-6 (IL-6), playing an important regulatory role in the acute phase of inflammation/infection processes. The CRP level in healthy individuals is usually very … Read more
Article Highlights RNA-binding proteins regulate post-transcriptional gene translation, but the macrophage-specific role of Zc3h12c remains unclear. Here, we characterized the role of Zc3h12c in macrophages using Tnfrsf11aCre-Zc3h12cflox/flox mice. Both Tnfrsf11a and Zc3h12c are highly expressed in renal tissues of patients with chronic kidney disease and are positively correlated with interstitial fibrosis scores. Single-cell RNA sequencing … Read more
[Image] Cover Image | Pixabay Written by | Song Wenfa Cancer and cardiovascular diseases are the leading causes of death worldwide, and these two types of diseases are associated with inflammatory risk factors. Inflammation plays a significant role in the occurrence and development of cancer and cardiovascular diseases. Micronutrients, such as vitamins and minerals, are … Read more