Key Details Not to Ignore in ADC Drug Treatment

Key Details Not to Ignore in ADC Drug Treatment

Click below to follow and learn more about anti-cancer knowledge 👇 For patients with HER2 mutations in non-small cell lung cancer, past treatments have primarily involved chemotherapy, immunotherapy combined with chemotherapy, and anti-angiogenic therapy combined with chemotherapy. With the rise of antibody-drug conjugates (ADC), the treatment prospects for HER2 mutation patients are becoming increasingly clear. … Read more

A Journey into ADC Innovation

A Journey into ADC Innovation

After 2019, ADC drugs have been approved for marketing one after another, and the approval of Aidiqi in 2021 marked a milestone in the development of domestic ADC innovative drugs. The broad therapeutic prospects and huge market size have stimulated many pharmaceutical companies to ignite their enthusiasm for ADC drug research and development, leading the … Read more

What Are ADC Drugs? Which Breast Cancer Patients Can Receive ADC Treatment?

What Are ADC Drugs? Which Breast Cancer Patients Can Receive ADC Treatment?

Breast cancer, regarded as the “killer of beauty,” is a malignant tumor that severely threatens women’s health, with an increasing incidence year by year. Antibody-drug conjugates (ADC), as a new type of therapeutic drug, have become a hot research topic in the field of breast cancer due to their advantages of “high efficacy and low … Read more

What Magic Do ADCs and RDCs Hold?

What Magic Do ADCs and RDCs Hold?

ADCs (Antibody-Drug Conjugates) and RDCs (Radionuclide Conjugates) are innovative drugs that have gained significant attention in recent years, demonstrating enormous potential in the field of oncology. They are referred to as the “magic bullets” of tumor-targeted therapy because they enable precise treatment while avoiding damage to normal cells. ADC drugs link antibodies with known effective … Read more

Understanding Antibody-Drug Conjugates (ADCs) in Lung Cancer Treatment

Understanding Antibody-Drug Conjugates (ADCs) in Lung Cancer Treatment

Last week, while introducing the “Breakthroughs and Innovations in Lung Cancer Treatment” from the “AACR 2021 Annual Report on Anti-Cancer Progress”(>> Click to review), I mentioned a popular research topic—Antibody-Drug Conjugates (ADCs), which saw two new ADCs approved and two ADCs expanding their indications in 2021. Some readers expressed a desire to learn more about … Read more

Mechanisms of ADC Resistance and Countermeasures

Mechanisms of ADC Resistance and Countermeasures

ADC (Antibody-drug conjugate) is a new type of drug for cancer treatment. It is a complex formed by combining anti-tumor drugs with antibodies, allowing for precise delivery of the drug into tumor cells, thereby achieving targeted treatment of tumor cells. However, with the widespread application of ADCs, research has found that the issue of ADC … Read more

The Development Momentum of ADC Drugs

The Development Momentum of ADC Drugs

Source: YaoDu Written by: -7℃ Edited by: Wanzi ADC (Antibody Drug Conjugate) is a complex formed by linking cytotoxic drugs to monoclonal antibodies targeting tumors, which combines the characteristics of targeted drugs and chemotherapy drugs, enabling precise treatment. The concept of ADC drugs was proposed as early as 1900, but it remained theoretical for a … Read more

Combination Therapy of Antibody-Drug Conjugates (ADCs)

Combination Therapy of Antibody-Drug Conjugates (ADCs)

Introduction Antibody-drug conjugates (ADCs) are formed by linking monoclonal antibodies that target specific antigens with small molecule cytotoxic drugs through linkers, combining the powerful killing effect of traditional small molecule chemotherapy with the tumor targeting ability of antibody drugs.ADCs consist of three main components: the antibody responsible for selectively recognizing cancer cell surface antigens, the … Read more

What Exactly Is an ADC?

What Exactly Is an ADC?

Known as magic bullets, ADCs have been highly praised in recent years. The design concept of these drugs is clear: to utilize the high specificity of antigen-antibody binding to selectively deliver toxins to antigen-positive cells, thereby selectively killing target cells and reducing damage to normal cells. However, like other drugs, the actual performance of ADCs … Read more

Research on ADC Combination Therapy

Research on ADC Combination Therapy

Introduction Antibody-drug conjugates(ADC) are formed by linking monoclonal antibodies targeting specific antigens with small molecule cytotoxic drugs through linkers, combining the powerful killing effect of traditional small molecule chemotherapy with the tumor targeting ability of antibody drugs. ADC consists of three main components: the antibody responsible for selectively recognizing cancer cell surface antigens, the drug … Read more