All data originates from analog signals. Analog chips are integrated analog circuits used to process analog signals. Analog signals are continuous in both time and amplitude, while digital signals are discontinuous in both time and amplitude. External signals are converted into electrical signals by sensors, which are analog signals, and further processed in systems composed … Read more
What Is Ultrasonic Testing DAC/TCG Curve? What Is Ultrasonic Testing DAC/TCG Curve? DAC Curve Concept: DAC=Distance Amplitude Curve The DAC curve, or “Distance-Amplitude Curve”, represents the relationship between the amplitude of echo signals and the distance of the ultrasonic waves. For defects of the same size, the echo amplitude varies due to different sound path … Read more
0 Introduction Before discussing Analog to Digital Converters (ADC) and Digital to Analog Converters (DAC), let’s first clarify what analog signals and digital signals are. Analog signals can be understood as physical quantities from the real world, but these quantities are electrical signals. For example, radio signals, etc. The characteristics of analog signals are that … Read more
01 DAC‘s Emergence and Advantages Cancer therapeutics need to balance efficacy and safety, even targeted chemotherapy does not always only kill abnormal cancer cells, and non-specific toxicity can lead to a low therapeutic index and side effects. The technology of Proteolysis-targeting chimeras (PROTACs), which achieve therapeutic effects by promoting the degradation of target proteins, is … Read more
With the popularity of electronic products, there is a growing demand for digital systems to connect with the analog world to achieve changes, leading to an increasing need for Digital-to-Analog Converters (DACs). While designers are familiar with traditional voltage output DACs, many applications require current output DACs to provide precise, stable, high-resolution currents (tens or … Read more
Click below to follow and learn more about anti-cancer knowledge 👇 For patients with HER2 mutations in non-small cell lung cancer, past treatments have primarily involved chemotherapy, immunotherapy combined with chemotherapy, and anti-angiogenic therapy combined with chemotherapy. With the rise of antibody-drug conjugates (ADC), the treatment prospects for HER2 mutation patients are becoming increasingly clear. … Read more
After 2019, ADC drugs have been approved for marketing one after another, and the approval of Aidiqi in 2021 marked a milestone in the development of domestic ADC innovative drugs. The broad therapeutic prospects and huge market size have stimulated many pharmaceutical companies to ignite their enthusiasm for ADC drug research and development, leading the … Read more
Introduction Antibodies are one of the key components of ADC drugs, serving as precise guiding components with the functions of targeting and toxin delivery. They can specifically recognize the target antigens on the surface of tumor cells, delivering toxins to the tumor cells and mediating the localization and endocytosis of ADCs in tumor cells[1]. After … Read more
GUIDE Editor’s Recommendation Antibody-drug conjugates (ADC) remained popular in 2022. Enhertu redefined the treatment landscape for HER2 breast cancer, making headlines at major academic conferences like ASCO and ESMO; Kelun-Biotech approached a $10 billion license-out deal with multinational pharmaceutical company Merck, setting a new record for local pharmaceutical companies going abroad; the world’s first anti-CD79b … Read more
The Concept and Development History of ADC The treatment of tumors has always undergone a continuous transformation from theory to application, breaking and transforming again. As early as a century ago, scholars proposed the concept of antibody-drug conjugates (ADCs), vividly calling them “magic bullets,” aimed at targeting specific antigens that may exist on the surface … Read more