Lung Cancer

A Detailed Explanation of ADC: How ADC is Reshaping Clinical Guidelines? A New Era in Lung Cancer Treatment

by
A Detailed Explanation of ADC: How ADC is Reshaping Clinical Guidelines? A New Era in Lung Cancer Treatment

In 2019, a CT imaging comparison from Gustave Roussy Hospital in Paris, France, caused a stir in the oncology community: a late-stage non-small cell lung cancer patient, who had failed both chemotherapy and immunotherapy, showed significant reduction in systemic metastatic lesions just two months after being enrolled in the clinical trial of Trastuzumab Deruxtecan (T-DXd), … Read more

Key Details Not to Ignore in ADC Drug Treatment

by
Key Details Not to Ignore in ADC Drug Treatment

Click below to follow and learn more about anti-cancer knowledge 👇 For patients with HER2 mutations in non-small cell lung cancer, past treatments have primarily involved chemotherapy, immunotherapy combined with chemotherapy, and anti-angiogenic therapy combined with chemotherapy. With the rise of antibody-drug conjugates (ADC), the treatment prospects for HER2 mutation patients are becoming increasingly clear. … Read more

Understanding Antibody-Drug Conjugates (ADCs) in Lung Cancer Treatment

by
Understanding Antibody-Drug Conjugates (ADCs) in Lung Cancer Treatment

Last week, while introducing the “Breakthroughs and Innovations in Lung Cancer Treatment” from the “AACR 2021 Annual Report on Anti-Cancer Progress”（>> Click to review）, I mentioned a popular research topic—Antibody-Drug Conjugates (ADCs), which saw two new ADCs approved and two ADCs expanding their indications in 2021. Some readers expressed a desire to learn more about … Read more

A Detailed Explanation of ADC Drugs: Innovative Therapies for Lung Cancer

by
A Detailed Explanation of ADC Drugs: Innovative Therapies for Lung Cancer

Antibody-drug conjugates (ADC), also known as “magic bullets,” use monoclonal antibodies (Antibody) to deliver small molecule drugs (Drug) directly to tumor cells expressing specific antigens through a linker (Conjugate). In recent years, ADC drugs have rewritten the treatment guidelines for blood cancers, breast cancer, ovarian cancer, and lung cancer, providing patients with significantly improved clinical … Read more

Understanding ADCs: A Comprehensive Guide

by
Understanding ADCs: A Comprehensive Guide

Introduction Antibody-Drug Conjugates (ADCs) are targeted therapies that consist of antibodies, linkers, and cytotoxic drugs, using monoclonal antibodies as carriers to efficiently deliver cytotoxic drugs to target tumor cells in a targeted manner, combining the powerful killing effect of traditional chemotherapy with the tumor-targeting capability of antibody drugs. An ideal ADC maintains stability in the … Read more