drug delivery

A Novel 3D Printed Antibiotic-Loaded Intraocular Lens: A Breakthrough for Post-Cataract Endophthalmitis Patients!

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A Novel 3D Printed Antibiotic-Loaded Intraocular Lens: A Breakthrough for Post-Cataract Endophthalmitis Patients!

Ophthalmology Innovative Approach New Antibiotic-Loaded Intraocular Lens Effectively Prevents and Treats Post-Cataract Endophthalmitis Postoperative endophthalmitis is a serious complication of ocular surgery that can lead to vision loss and globe atrophy, commonly occurring after cataract surgery, with an incidence rate of 0.012% to 1.3% globally over the past 20 years. Current preventive methods for endophthalmitis … Read more

The Internet of Everything | Small Size, Big Uses: Micro Robots Transition from Science Fiction to Reality

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The Internet of Everything | Small Size, Big Uses: Micro Robots Transition from Science Fiction to Reality

Author | Yufei Men Editor | New Story First Published | Global Intelligent Business ▍Image Source: Internet In the internet era, people often use the term “brain hole” to describe some of the strange ideas from netizens. In fact, even before the internet appeared, there were plenty of “brain holes”. For example, the Hollywood movie … Read more

Weight Capacity Exceeding 20 Times Its Own! Microrobots Can Deliver Drugs Inside the Human Body

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Weight Capacity Exceeding 20 Times Its Own! Microrobots Can Deliver Drugs Inside the Human Body

Introduction Microrobots can deliver drugs inside the human body On May 31, reported by Wang Ziyu, taking medicine is one of the necessary experiences in life, but for many children and even some adults, taking medicine can be a very difficult task. Additionally, some individuals cannot effectively absorb the medication due to physical reasons. To … Read more

Applications of Microrobots in Medical Systems: A Comprehensive Analysis from Design to Practice

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Applications of Microrobots in Medical Systems: A Comprehensive Analysis from Design to Practice

In this issue, the author introduces the entire process of design to application of microrobots in medical systems, discussing the current technological level and the challenges faced. Microrobots, ranging in size from a few micrometers to several millimeters, can access complex anatomical areas within the human body that are difficult to reach, enabling targeted drug … Read more

Zhejiang University Professors Cheng Kui and Cai Xiujun Publish in ACS Nano: Multifunctional Double-Loaded Oral Nanoplatform for Computed Tomography Imaging-Guided Integrated Treatment of Inflammatory Bowel Disease

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Zhejiang University Professors Cheng Kui and Cai Xiujun Publish in ACS Nano: Multifunctional Double-Loaded Oral Nanoplatform for Computed Tomography Imaging-Guided Integrated Treatment of Inflammatory Bowel Disease

Excessive reactive oxygen species, damage to the epithelial barrier, immune dysregulation, and imbalance of the gut microbiota are key factors leading to the onset of inflammatory bowel disease (IBD) and complicating its treatment. Timely diagnosis of the disease and precise delivery of therapeutic drugs to the inflamed intestinal sites is a targeted strategy that can … Read more

Transforming Bacteria into Microrobots for Targeted Drug Delivery in Cancer Treatment under Magnetic Navigation

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Transforming Bacteria into Microrobots for Targeted Drug Delivery in Cancer Treatment under Magnetic Navigation

Written by丨Wang CongEdited by丨Wang DuoyuTypeset by丨Shui ChengwenBacteria are attracted to chemical gradients, such as low oxygen levels or high acidity, which are commonly found near tumor tissues. Injecting bacteria near tumor tissues for cancer treatment is known as bacterial-mediated tumor therapy.Bacteria accumulate in tumor tissues and grow within them, activating the patient’s immune system to … Read more

The First Triple-Payload ADC?

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The First Triple-Payload ADC?

The abstract from AACR hides a new modality. Following yesterday’s TCE conjugated ADC, there is also the Triple-payload ADC project submitted by Araris. Currently, only the abstract has been released, indicating that this is an ADC molecule targeting Nectin-4, designed with MMAE and dual Topo1i as a triple payload. Below is the full abstract:Araris’s site-specific … Read more

Understanding TCP Through a Historical Analogy

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Understanding TCP Through a Historical Analogy

Introduction: This article aims to discuss knowledge about TCP. Please forgive any inappropriate metaphors. In the fourth year of the Tianqi era of the Ming Dynasty, early morning. As dawn broke, I drove a horse-drawn cart full of goods to the South City Gate, which was the central location for handling goods. A line of … Read more

Degrader-Antibody Conjugates: Risks on the Path from Concept to Reality

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Degrader-Antibody Conjugates: Risks on the Path from Concept to Reality

01 DAC‘s Emergence and Advantages Cancer therapeutics need to balance efficacy and safety, even targeted chemotherapy does not always only kill abnormal cancer cells, and non-specific toxicity can lead to a low therapeutic index and side effects. The technology of Proteolysis-targeting chimeras (PROTACs), which achieve therapeutic effects by promoting the degradation of target proteins, is … Read more

One-Step Formation Method of Sperm-Like Structure Microrobots for Drug Delivery

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One-Step Formation Method of Sperm-Like Structure Microrobots for Drug Delivery

Sperm-Like Microrobots have broad application prospects in biomedicine, especially in precise drug delivery and minimally invasive surgery. However, traditional microrobots face challenges such as complex manufacturing processes, high material requirements, and poor environmental adaptability. Professor Shen Yajing’s research team at the Hong Kong University of Science and Technology proposed a vortex turbulence-assisted microfluidic platform (VTAM) … Read more