Multicomponent Herbal Small Molecule Hydrogels for TBI Treatment

Multicomponent Herbal Small Molecule Hydrogels for TBI Treatment

iNature Self-assembling hydrogels for mechanical support and drug delivery have been widely studied in the context of traumatic brain injury (TBI). However, most self-assembling hydrogels rely on polymer carriers or the introduction of exogenous inactive substances, often raising biosafety concerns and making clinical translation difficult. On October 9, 2024, a research paper titled “Small Molecule … Read more

Cold Exposure Therapy Enhances Breast Cancer Treatment

Cold Exposure Therapy Enhances Breast Cancer Treatment

iNature Cold exposure therapy (CE) is a low-cost, non-invasive treatment for malignant tumors. When the body is exposed to a cold environment, it activates the thermogenic metabolism of brown adipose tissue (BAT), quickly inducing tumor starvation and inhibiting tumor growth. The microenvironmental changes caused by CE can further complement conventional treatments (such as radiotherapy and … Read more

Building a Portable PyPI Server with Raspberry Pi

Building a Portable PyPI Server with Raspberry Pi

In this article, I will discuss how to clone the PyPI repository onto a Raspberry Pi and provide content so that connected devices can install dependencies using the <span>pip install</span> command without an internet connection. Objective There are many ways to create your own PyPI mirror, and my method may be suitable for everyone now. … Read more

Self-Oxygenating & Glutathione-Depleting Microneedle Patch for Photodynamic Therapy of Tumors

Self-Oxygenating & Glutathione-Depleting Microneedle Patch for Photodynamic Therapy of Tumors

Photodynamic therapy (PDT), as a non-invasive treatment for tumors, has garnered widespread attention. However, the hypoxia of solid tumors, the skin phototoxicity of “always-on” photosensitizers (PSs), and the abundant supply of glutathione (GSH) in cancer cells severely hinder the clinical application of PDT. To address this issue, the team from the First Affiliated Hospital of … Read more

Brain-Inspired Computing Needs A Master Plan

Brain-Inspired Computing Needs A Master Plan

Introduction With the increasing demand for computing power, the energy consumption of modern computing systems is also rising, making it challenging to support the sustainable future development of artificial intelligence technologies. This energy issue largely stems from the traditional digital computing systems employing the classic von Neumann architecture, where data processing and storage occur in … Read more

Using Holographic 3D Imaging to Observe Virus-Induced Cytopathic Effects

Using Holographic 3D Imaging to Observe Virus-Induced Cytopathic Effects

Cytopathic effects (CPEs) are a hallmark of infection. Due to the phototoxicity of classical optical microscopy, CPEs are difficult to observe. This study reports different patterns of viral infection in live cells using Digital HoloTomographic Microscopy (DHTM). DHTM is label-free and records the phase shift of low-energy light passing through the sample on a transparent … Read more

Salt Anion Amphiphilicity-Activated Electrolyte Cosolvent Selection Strategy for Durable Zn Metal Anode

Salt Anion Amphiphilicity-Activated Electrolyte Cosolvent Selection Strategy for Durable Zn Metal Anode

[Research Background] Aqueous zinc-ion batteries have good application prospects in large-scale energy storage due to their high safety and low cost. However, the corrosion of zinc metal in aqueous electrolytes, as well as the growth of zinc dendrites during deposition, leads to low coulombic efficiency and cycling stability of the zinc metal anode, severely hindering … Read more

Integrated Multifunctional Wearable Platform with Graphene and Liquid Metal

Integrated Multifunctional Wearable Platform with Graphene and Liquid Metal

Research Background Continuous wearable monitoring devices and systems are crucial not only for diagnosing physical conditions but also for predicting pathological states, enabling early and effective interventions. Accelerometers are essential components in many electronic systems, from consumer electronics to healthcare systems. Traditional wearable motion devices are inherently inflexible and unsuitable for seamless integration with the … Read more

Photothermal Driven Chitosan-Stabilized MoS2 Nanosheets for Wound Healing

Photothermal Driven Chitosan-Stabilized MoS2 Nanosheets for Wound Healing

iNature Enzymatic MoS2 faces challenges such as unstable dispersion, low solubility, and biotoxicity in tissue repair. On September 21, 2024, researchers from Sichuan University, Sun Yong and Han Xianglong, published a paper titled “Engineering Injectable Coassembled Hydrogel by Photothermal Driven Chitosan-Stabilized MoS2 Nanosheets for Infected Wound Healing” in ACS Nano. The study designed an injectable … Read more

Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound

Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound

Source Qian Zhang, Jiaxing Wang, Yanjun Ding, et al. Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound. Chinese Journal of Medical Imaging, 2020, 28(12): 907-911+917 Abstract Objective To explore the ability of the phase-change nanoparticles (Ce6@PFP/PLGA NPs) loaded with the sonosensitizer Chlorin e6 (Ce6) and perfluoropentane (PFP) combined with low-intensity … Read more