iNature Due to the non-invasive remote driving and drug loading capabilities of magnetic nanorobots, there are broad application prospects in thrombolytic therapy. Although nanorobots smaller than 100 nanometers are suitable for microvascular systems, their propulsion performance is severely affected due to limited response to magnetic fields. On October 18, 2024, Cheng Yu and He Bin … Read more
Shandong Provincial Medical Association of Ultrasound Submission Date: 2022-11-01 Corresponding Author: Li Jie, Email: [email protected]. Abstract:Nano-ultrasound contrast agents possess unique features such as liquid-gas phase transition and acoustic cavitation effects, making them important potential carriers for siRNA delivery. Currently, siRNA loading is mainly achieved through electrostatic attraction, requiring the construction of positively charged contrast agents … Read more
This article is reproduced from the WeChat public account “Tianjin Medical University” Fang Zhongze Professor at Tianjin Medical University, PhD supervisor, Vice Dean of the School of Public Health, Executive Deputy Director of the National Preventive Medicine Experimental Teaching Center, Director of the Department of Health Toxicology and Health Inspection and Quarantine, and Deputy Director … Read more
iNature The photodynamic therapy (PDT) using oxygen-dependent type II photosensitizers is often limited by the hypoxic microenvironment of solid tumors. Type I photosensitizers generate oxygen-independent reactive oxygen species (ROS) under light irradiation, but they suffer from aggregation-caused quenching (ACQ) and low ROS generation efficiency. On December 19, 2024, the team led by Ge Zhishen from … Read more
iNature Activating the STING pathway in the cytosol of tumor-infiltrating antigen-presenting cells (APCs) can trigger an effective antitumor immune response for cancer treatment. However, most STING agonists are hydrophilic small molecules that face rapid clearance and poor cytosolic delivery issues after systemic administration. Although various nanoparticles have been developed to facilitate cytosolic delivery, they often … Read more
Research progress of polyimide as electrode materials for supercapacitors DING Chengcheng ,YU Juan ,HUANG Pei ,WANG Xiaodong （State Key Laboratory of Materials-Oriented Chemical Engineering，College of Chemical Engineering，Nanjing Tech University，Nanjing 211800，China） DOI：10.3969/j.issn.1001-3539.2024.01.025 Fund Information： National Natural Science Foundation Project (22035007) Abstract: The application advantages of supercapacitors and the development and characteristics of its electrode were briefly … Read more
iNature The stimulator of interferon genes (STING) pathway shows great potential in reshaping the immunosuppressive tumor microenvironment and initiating anti-tumor immunity. However, effectively activating STING while avoiding toxic side effects from systemic administration remains challenging. On January 7, 2025, a communication from Li Weimin’s team at Sichuan University was published online in ACS Nano titled … Read more
[Research Background] In traditional metal oxide cathode materials during charge and discharge processes, the insertion/extraction of alkali metal (lithium, sodium, potassium, etc.) ions requires charge compensation provided by transition metals, meaning that oxidation-reduction reactions occur as electrons are gained and lost. The number of electrons that can be transferred is one of the main limiting … Read more
01 Overview Disadvantages of Existing Technology: The gear in the aircraft engine, as a key component for power transmission, can lead to fuel line issues and power interruptions if it fails, posing a serious risk to flight safety. Therefore, condition monitoring is particularly important. Current gear fault detection methods rely on vibration sensors, but aircraft … Read more
Programmed cell death (PCD) plays a crucial role in triggering tumor cell death in the forefront of biomedical research. However, due to various drug resistance mechanisms in cancer, malignant tumor cells often develop resistance to commonly used apoptosis-inducing anticancer drugs. Considering that mitochondria are the sources of aerobic respiration and reactive oxygen species (ROS), we … Read more