Fluorescent Probes and Imaging Agents Based on Twisted Intramolecular Charge Transfer (TICT)

Fluorescent Probes and Imaging Agents Based on Twisted Intramolecular Charge Transfer (TICT)

1. Introduction Since Sir George Gabriel Stokes proposed the concept of fluorescence in 1845 and subsequent reports of fluorescence observed in natural compounds, the modern theoretical understanding of fluorescence has begun to form and continues to develop to this day. The characteristic features of fluorescence make it a potential tool for the visual detection of … Read more

Small Molecule Photoacoustic Probes

Small Molecule Photoacoustic Probes

As a powerful tool for understanding key life processes, molecular imaging enables rapid, non-invasive, real-time visualization of biological events in vivo. Its outstanding performance in various biomedical fields demonstrates broad application potential. Currently, technologies based on fluorescence imaging, magnetic resonance imaging (MRI), and positron emission tomography (PET) have achieved significant breakthroughs in the study of … Read more

3D Printed Microrobots: Navigating, Temperature Sensing, and Treating Diseases Inside the Body, Advancing Precision Medicine

3D Printed Microrobots: Navigating, Temperature Sensing, and Treating Diseases Inside the Body, Advancing Precision Medicine

Background Introduction Can you imagine? A robot smaller than a hair strand that can “navigate itself” inside the body, report its location in real-time, and precisely “burn” tumor cells? This is not a science fiction scenario, but the latest research published in Advanced Materials. This microrobot, known as TriMag, disrupts traditional medicine with three “superpowers”: … Read more

Organic Radiosensitizer with Aggregation-Induced Emission Characteristics for Tumor Ablation through Synergistic Apoptosis and Immunogenic Cell Death

Organic Radiosensitizer with Aggregation-Induced Emission Characteristics for Tumor Ablation through Synergistic Apoptosis and Immunogenic Cell Death

This study explores the application of pure organic nanoparticles in tumor therapy, particularly their potential in photothermal radiotherapy combined treatment. The background of the article points out that the hypoxic state of the tumor microenvironment is a significant reason for radiotherapy resistance, while photothermal therapy can improve the hypoxic state and enhance the radiotherapy effect … Read more

ACS Nano | Organic Radiotherapy Sensitizers with AIE Characteristics Achieve Tumor Ablation through Synergistic Induction of Apoptosis and Immunogenic Cell Death

ACS Nano | Organic Radiotherapy Sensitizers with AIE Characteristics Achieve Tumor Ablation through Synergistic Induction of Apoptosis and Immunogenic Cell Death

Inspired by the clinical enhancement of radiotherapy efficacy through hyperthermia, this study demonstrates a pure organic nanoparticle’s multimodal diagnostic application in tumor combination therapy, integrating imaging and photothermal properties. This nanoparticle possesses various unique characteristics and functions, including excellent photostability and thermal stability, strong fluorescence emission in the near-infrared II (NIR-II) region, extremely high photothermal … Read more

Photothermal Driven Chitosan-Stabilized MoS2 Nanosheets for Wound Healing

Photothermal Driven Chitosan-Stabilized MoS2 Nanosheets for Wound Healing

iNature Enzymatic MoS2 faces challenges such as unstable dispersion, low solubility, and biotoxicity in tissue repair. On September 21, 2024, researchers from Sichuan University, Sun Yong and Han Xianglong, published a paper titled “Engineering Injectable Coassembled Hydrogel by Photothermal Driven Chitosan-Stabilized MoS2 Nanosheets for Infected Wound Healing” in ACS Nano. The study designed an injectable … Read more

Near-Infrared-Induced Photothermal-Pyroelectric Synergy for Enhanced Sensing Performance

Near-Infrared-Induced Photothermal-Pyroelectric Synergy for Enhanced Sensing Performance

Article Information Near-Infrared-Induced Photothermal-Pyroelectric Synergy Promotes Flexible Sensing Platform Photoelectrochemical Analysis Performance First Author: Li Lin Corresponding Authors: Cui Kang*, Zhang Lina*, Yu Jinghua* Affiliation: Jinan University Research Background Exploring and regulating the photothermal material-driven pyroelectric effect may bring great potential for next-generation in vitro instant diagnostics. In pursuing this goal, the powerful impact of … Read more

Thiophene π-Bridge Manipulation of NIR-II AIEgens for Multimodal Tumor Phototheranostics

Thiophene π-Bridge Manipulation of NIR-II AIEgens for Multimodal Tumor Phototheranostics

Fu Rui Sen Na Mi N A N O NIR-Ⅱ FLI Thiophene π-Bridge Manipulation of NIR-II AIEgens for Multimodal Tumor Phototheranostics Journal:Angewandte Chemie-International Edition, IF=16.1 Pub Date:2024-02-12 First Author:Yixiong Gui, Yuanwei Wang, Deliang Wang Corresponding Authors:Dingyuan Yan*, Ben Zhong Tang*, and Dong Wang* Corresponding Author Institution: School of Science and Engineering, Shenzhen Institute of Aggregate … Read more