tumor treatment

Organic Radiosensitizer with Aggregation-Induced Emission Characteristics for Tumor Ablation through Synergistic Apoptosis and Immunogenic Cell Death

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Organic Radiosensitizer with Aggregation-Induced Emission Characteristics for Tumor Ablation through Synergistic Apoptosis and Immunogenic Cell Death

This study explores the application of pure organic nanoparticles in tumor therapy, particularly their potential in photothermal radiotherapy combined treatment. The background of the article points out that the hypoxic state of the tumor microenvironment is a significant reason for radiotherapy resistance, while photothermal therapy can improve the hypoxic state and enhance the radiotherapy effect … Read more

ACS Nano | Organic Radiotherapy Sensitizers with AIE Characteristics Achieve Tumor Ablation through Synergistic Induction of Apoptosis and Immunogenic Cell Death

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ACS Nano | Organic Radiotherapy Sensitizers with AIE Characteristics Achieve Tumor Ablation through Synergistic Induction of Apoptosis and Immunogenic Cell Death

Inspired by the clinical enhancement of radiotherapy efficacy through hyperthermia, this study demonstrates a pure organic nanoparticle’s multimodal diagnostic application in tumor combination therapy, integrating imaging and photothermal properties. This nanoparticle possesses various unique characteristics and functions, including excellent photostability and thermal stability, strong fluorescence emission in the near-infrared II (NIR-II) region, extremely high photothermal … Read more

Design Mechanisms and Adverse Reaction Management of Antibody-Drug Conjugates (ADCs)

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Design Mechanisms and Adverse Reaction Management of Antibody-Drug Conjugates (ADCs)

Introduction: Antibody-drug conjugates (ADC) consist of antibodies, linkers, and small molecule cytotoxic drugs, combining high specificity and high cytotoxicity advantages. However, their structural diversity and complexity, along with the low content of released small molecule toxins in the circulatory system, pose significant challenges for pharmacokinetic studies. This article will discuss the mechanisms, design, safety features, … Read more

Cold Exposure Therapy Enhances Breast Cancer Treatment

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Cold Exposure Therapy Enhances Breast Cancer Treatment

iNature Cold exposure therapy (CE) is a low-cost, non-invasive treatment for malignant tumors. When the body is exposed to a cold environment, it activates the thermogenic metabolism of brown adipose tissue (BAT), quickly inducing tumor starvation and inhibiting tumor growth. The microenvironmental changes caused by CE can further complement conventional treatments (such as radiotherapy and … Read more

High Load Medical Robots: Radiation Therapy and Virtual Surgical Knife

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High Load Medical Robots: Radiation Therapy and Virtual Surgical Knife

整理丨朱光明 Just looking at this title is frightening. For tumor treatment, robots with a load capacity of 50–300 kilograms have already begun to be applied in heavy medical scenarios. For example, the KUKA robot shared in our video is an example of patient positioning and precise tumor radiation therapy or X-ray examination. The C-arm X-ray … Read more