Design Mechanisms and Adverse Reaction Management of Antibody-Drug Conjugates (ADCs)

Design Mechanisms and Adverse Reaction Management of Antibody-Drug Conjugates (ADCs)

Introduction: Antibody-drug conjugates (ADC) consist of antibodies, linkers, and small molecule cytotoxic drugs, combining high specificity and high cytotoxicity advantages. However, their structural diversity and complexity, along with the low content of released small molecule toxins in the circulatory system, pose significant challenges for pharmacokinetic studies. This article will discuss the mechanisms, design, safety features, … Read more

Cold Exposure Therapy Enhances Breast Cancer Treatment

Cold Exposure Therapy Enhances Breast Cancer Treatment

iNature Cold exposure therapy (CE) is a low-cost, non-invasive treatment for malignant tumors. When the body is exposed to a cold environment, it activates the thermogenic metabolism of brown adipose tissue (BAT), quickly inducing tumor starvation and inhibiting tumor growth. The microenvironmental changes caused by CE can further complement conventional treatments (such as radiotherapy and … Read more

High Load Medical Robots: Radiation Therapy and Virtual Surgical Knife

High Load Medical Robots: Radiation Therapy and Virtual Surgical Knife

整理丨朱光明 Just looking at this title is frightening. For tumor treatment, robots with a load capacity of 50–300 kilograms have already begun to be applied in heavy medical scenarios. For example, the KUKA robot shared in our video is an example of patient positioning and precise tumor radiation therapy or X-ray examination. The C-arm X-ray … Read more