Sonodynamic Therapy (SDT) is a novel non-invasive tumor treatment method that utilizes ultrasound to activate sonosensitizers to generate reactive oxygen species (ROS) to induce tumor cell death. Based on the deep tissue penetration capability of ultrasound, SDT can treat deep tumors and has broad clinical transformation prospects. The main mechanism of SDT is the generation … Read more
Source Qian Zhang, Jiaxing Wang, Yanjun Ding, et al. Inhibition of Breast Cancer Cells by Novel Nanoparticles Combined with Low-Intensity Focused Ultrasound. Chinese Journal of Medical Imaging, 2020, 28(12): 907-911+917 Abstract Objective To explore the ability of the phase-change nanoparticles (Ce6@PFP/PLGA NPs) loaded with the sonosensitizer Chlorin e6 (Ce6) and perfluoropentane (PFP) combined with low-intensity … Read more
Sonodynamic therapy (SDT) is a non-invasive treatment method based on reactive oxygen species (ROS) that interacts with ultrasound (US) activated sonosensitizers and surrounding oxygen and water molecules to produce highly cytotoxic ROS and induce apoptosis. Due to its ability to penetrate deep tissues while causing minimal damage to normal cells, it has significant potential in … Read more