In previous discussions about dual payloads, it was mentioned that payload diversity is a crucial consideration in the future development of ADCs (ADC: Payload Evolution and Dual Payload Strategy). There are two main reasons for this: first, the existing toxin payloads have relatively singular modes of action, and treatment strategies after drug resistance need to … Read more
(Get Happy!~) Although many users of the little assistants have gradually faded out of the Summoner’s Rift, after the college entrance examination, quite a few people have logged back into LOL, returning to where the dream began. However, after the update to version 8.11 of League of Legends, players who enjoy playing ADC were surprised … Read more
Among the 12 ADC drugs approved by the FDA, 5 utilize Seagen’s VC-MMAE linker toxin platform. As a pioneer in global ADC drug development, one might ask if Seagen has any regrets?They might respond that they missed the opportunity to develop ADC drugs targeting the classic targets HER2 and EGFR, and instead, they can only … Read more
Updates on the first human study data from Phase I/II show that B7-H3 targeted ADCs continue to demonstrate therapeutic potential. In recent years, antibody-drug conjugates (ADCs) have emerged as a new class of drugs that bring new “hope” to the treatment of advanced cancer patients due to their unique mechanisms of action. The B7 family … Read more
▎Armstrong The 2025 American Association for Cancer Research (AACR) Annual Meeting will be held from April 25-30 in Chicago, USA. Recently, the conference abstracts have been released, showcasing a significant presence of Chinese innovations. In the field of ADCs, the majority of reports come from Chinese pharmaceutical companies, with nearly 100 innovative ADCs covering various … Read more
If a few years ago, presenting a simple PowerPoint on the ADC field could impress without the need for future visions, cutting-edge technologies, or a vibrant pipeline forest, today, the ADC field requires substantial content to make an impact. This shift is attributed to advancements in industry technology and rising awareness. Data shows that from … Read more
There are many key indicators for measuring the quality of an oscilloscope testing system, and the “Effective Number of Bits (ENOB)” is crucial for understanding the entire measurement system. This article will discuss the effective bits of oscilloscopes, the impact of ENOB on actual signal testing, and provide methods for solving it using EXCEL in … Read more
“Analyzing the working principles of digital-to-analog converters and analog-to-digital converters—from resistor ladder networks to Delta-Sigma modulation techniques.” Microcontrollers are “consuming” the entire world. Nowadays, even the most basic tasks like blinking an LED are cheaper and simpler with microcontrollers than building oscillating circuits with discrete components or relying on the once ubiquitous 555 timer chip. … Read more
Ground Noise Isolation and Reduction Solutions for High-Precision ADC Circuit PCBsHigh-precision analog-to-digital converters (ADCs) are widely used in industrial measurement, medical devices, and high-precision instruments. However, in actual circuit design, the performance of ADCs is often affected by PCB layout and ground noise, leading to signal distortion, reduced resolution, and even data errors. Therefore, reasonable … Read more
