What Are ADC Drugs? Which Breast Cancer Patients Can Receive ADC Treatment?

What Are ADC Drugs? Which Breast Cancer Patients Can Receive ADC Treatment?

Breast cancer, regarded as the “killer of beauty,” is a malignant tumor that severely threatens women’s health, with an increasing incidence year by year. Antibody-drug conjugates (ADC), as a new type of therapeutic drug, have become a hot research topic in the field of breast cancer due to their advantages of “high efficacy and low … Read more

In-Depth Analysis of Antibody-Drug Conjugates (ADC) – Part 3

In-Depth Analysis of Antibody-Drug Conjugates (ADC) - Part 3

Introduction Antibody-drug conjugates (ADCs) are “biological bullets” formed by conjugating cytotoxic drugs (payloads) to antibodies via a “linker.” They consist of five components: target, antibody, linker, payload, and conjugation method. Each part is crucial to the function of ADCs, but today we will focus on the linker that connects the antibody and payload, examining the … Read more

Comprehensive Interpretation of Antibody-Drug Conjugates (ADC)

Comprehensive Interpretation of Antibody-Drug Conjugates (ADC)

Since the first use of cytotoxic chemicals to treat cancer, oncologists have been searching for ways to enhance efficacy without significantly increasing overall toxicity to patients. One of the methods attempted to improve the killing effect on tumor cells is the use of cytotoxic agents with potency at picomolar or lower levels (such as microtubule … Read more

ADC Technology: Innovations from Five Key Elements

ADC Technology: Innovations from Five Key Elements

History of ADC Drug Development Phase 1 (1906-1982), the concept of targeted therapy was proposed, and the technology took shape. Phase 2 (1983-2011), transition from clinical trials to commercialization, Mylotarg® was approved for market. Phase 3 (2012-present), explosive growth of ADC products. The five key elements of ADC drugs are target, antibody, linker, cytotoxic agent, … Read more

Analysis of Hall Sensor Working Principle

Analysis of Hall Sensor Working Principle

The potential difference generated by the Hall effect is very small, often only a few microvolts. Therefore, Hall sensors often have a built-in high-gain operational amplifier and may be combined with other system circuits based on overall requirements. The overall architecture is shown below. Typically, the final output signals from Hall sensors can be either … Read more

Design of Portable Signal Acquisition System Based on FPGA and NAND Flash

Design of Portable Signal Acquisition System Based on FPGA and NAND Flash

Abstract: In response to the current issues of low sampling rates and poor portability in signal acquisition systems, a design for a high-speed portable signal acquisition system based on FPGA is proposed. This design uses an FPGA chip to control an analog-to-digital converter (ADC) chip for high-speed signal sampling, then stores the data in a … Read more

Low-Power High-Speed ADC Design by Dr. Zhan Mingtao

Low-Power High-Speed ADC Design by Dr. Zhan Mingtao

Special Edition of ISSCC 2022, Session 10 On the morning of June 10, the 24th session of Doctoral Innovation in “Chip” was held online, featuring the 10th session of the 【ISSCC 2022 Special Edition】.Dr. Zhan Mingtao from Tsinghua University was invited to give a presentation titled “Low-Power High-Speed ADC Design“. The report was simultaneously broadcasted … Read more

Essential Knowledge for Microcontroller Beginners (4)

Essential Knowledge for Microcontroller Beginners (4)

Introduction to Common Microcontroller Chips  STC Microcontroller  The microcontrollers from STC are primarily based on the 8051 core, representing a new generation of enhanced microcontrollers. The instruction set is fully compatible with traditional 8051, offering speeds 8 to 12 times faster, equipped with ADC, 4-channel PWM, dual serial ports, a unique global ID, good encryption, and strong … Read more

Useful Knowledge: Interesting Basic Experiments with Raspberry Pi Pico

Useful Knowledge: Interesting Basic Experiments with Raspberry Pi Pico

Last week, we drew a Raspberry Pi Pico for everyone, and today we have brought some experimental routines. This includes several basic experiments, along with code and results. ▌01 PI Pico Experiment Board The Raspberry Pi Pico Development Board Basic Testing[1] provides basic setup for the PI Pico development board. By installing the Thonny development … Read more

How to Use a Pointer Multimeter for AC and DC Voltage Measurement

How to Use a Pointer Multimeter for AC and DC Voltage Measurement

Click the blue text above to follow us Hello Dear students Our Dou Classroom is back ~ Welcome to this episode So this is how to measure AC and DC voltage with a pointer multimeter! If you can’t watch the video for now, don’t worry! The complete wiring connection steps are right below Want to … Read more