If you were to ask what the most fruitful achievement of China’s pharmaceutical industry has been over the past two years, ADC drugs would undoubtedly be considered “top-tier”. From the $2.6 billion licensing deal of Rongchang Biologics’ Vadastuximab in 2021, to the over $10 billion ADC collaboration between Kelun-Biotech and Merck in 2022, and then … Read more
First, I would like to report to all the teachers that after issuing the explanation of the “Nine National Policies” overnight in the village, the micro-cap stocks finally stopped their free fall, and many oversold stocks have rebounded strongly. My cousin has already won back the money lost yesterday.(The losses from Monday have not been … Read more
Since when has Vitamin C become a “miracle drug”? Many people, upon showing symptoms of a cold, hurry to drink a large glass of orange juice or take various Vitamin C supplements in hopes of completely driving away the pathogens. So, is Vitamin C really the “miracle drug” for colds? We need to start with … Read more
In the early 20th century, Paul Ehrlich first proposed the famous “magic bullet” theory, suggesting that drugs could be developed to specifically target pathogenic structures without harming normal tissues and cells. Subsequently, the concept of antibody-drug conjugates (ADCs) was introduced, combining the target specificity of monoclonal antibodies with the anti-tumor properties of cytotoxic molecules. After … Read more
In the early 20th century, Paul Ehrlich first proposed the famous “magic bullet” theory, suggesting that drugs could be developed to specifically target pathogens without affecting normal tissues and cells. Subsequently, the concept of antibody-drug conjugates (ADCs) was introduced, combining the target specificity of monoclonal antibodies with the anti-tumor properties of cytotoxic molecules. After decades … Read more
Since the end of 2019 and the beginning of 2020, I have been looking at ADCs, and I have discussed with many experts in the field, leading to many misunderstandings, and my understanding has been continuously refreshed. Many articles about ADCs exist, but many of them contain misunderstandings. Now, there are more successful and failed … Read more
Representative ADC Technology Platforms As a combination drug, any component of an ADC can be replaced or modified.Therefore, the ADC combination technology platform has significant extensibility, allowing for the iterative combination of a rich variety of products.The development history of internationally leading ADC companies is rooted in having a competitive platform.Table 1 lists several representative … Read more