Due to adjustments in the WeChat public account mechanism, please click the top“Chemical Instrument Network” → Click the “…” in the upper right corner → Set as ★ star to receive our updates in a timely manner www.chem17.com A fluorescent sensor is an optical detection device based on the phenomenon of fluorescence, which excites the … Read more
In 1913, H.J. Bagg from the National Cancer Institute in the United States bred the “Bagg albino” from a white original strain; in 1923, Mac Dowell conducted inbreeding; and in 1932, the 26th generation was obtained and named the BALB/c strain.The BALB/c mouse is difficult to distinguish from the “ICR” and “NIH” mice, all having … Read more
On August 15, 2025, the journal Nature Communications published an article titled “A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers” (靶向间变性淋巴瘤激酶（ALK）的人源化抗体药物偶联物搭载吡咯并苯二氮䓬有效载荷在ALK表达癌症中的疗效验证).This study developed a novel ALK-targeted antibody-drug conjugate CDX0239-PBD, which demonstrates significant anti-tumor activity and survival benefits in various ALK-expressing pediatric and adult tumor models (including neuroblastoma, … Read more
How busy are Chinese doctors? They are constantly on the go between departments, outpatient clinics, and operating rooms. During the pandemic, their workload has only increased, and they wish they could make every minute count.But there’s still the pressure of research!Without research results, graduation, promotions, and evaluations will have to wait indefinitely.Thus, they can only … Read more
Immunotherapy has revolutionized cancer treatment by mobilizing the body’s immune system to eliminate tumors. However, despite significant clinical success in certain types of liquid tumors, the efficacy of immunotherapy remains poor in most solid tumors. The tumor immune microenvironment (TIME) is complex and heterogeneous, with various immune components interacting, which is a major reason affecting … Read more
Cancer, as a highly heterogeneous disease, involves complex changes across multiple layers, including the genome, epigenome, transcriptome, proteome, and metabolome. In recent years, with the rapid development of high-throughput sequencing technologies, the integrated analysis of multi-omics data has provided unprecedented opportunities for cancer research. Deep learning (DL) technology can analyze high-dimensional datasets to discover new … Read more
Resource Overview EBSCO is a group company specializing in the distribution of print journals, electronic journal publications, and electronic literature database publishing. It represents over 260,000 print journals, more than 50 full-text journal databases, over 50 abstract databases, and nearly 10,000 electronic journals (of which nearly 8,000 can be searched for abstracts or full text … Read more
Source: PaperWeekly This article is about 2800 words long and is recommended to be read in 6 minutes. This article mainly introduces how a paper is born. Nothing will work unless you do. ——Maya Angelou This article mainly introduces how a paper is born. The basic information of the article is as follows: Paper Title: … Read more
Source: Sihoo Professional Edition Knowledge Case Others Essays Voices Researchers have discovered for the first time that Bluetooth signals can be used as fingerprints to track smartphones. Mobile devices such as smartphones, smartwatches, and fitness bands transmit signals at a rate of 500 Bluetooth beacons per minute. These beacons can be used for Apple’s “Find … Read more
Introduction Antibody-drug conjugates (ADC) are formed by linking monoclonal antibodies targeting specific antigens with small molecule cytotoxic drugs through linkers, combining the powerful killing effect of traditional small molecule chemotherapy with the tumor targeting ability of antibody drugs. Since ADCs first entered clinical trials in the mid-1990s, they have developed into a very successful oncology … Read more