bone regeneration

Goodbye Metal Plates! 3D Printing of Permanent Artificial Bones Achieves Large Segmental Mandibular Bone Regeneration

by

Repairing large bone defects caused by mandibular tumor resection or severe trauma poses challenges. The traditional method of “autologous bone grafting + metal plate fixation” has issues such as donor site damage, stress shielding, and imaging interference, while absorbable scaffolds struggle to achieve synchronized osteogenesis and degradation.Recently, a team led by Professor Jeremy M. Crook … Read more

Recent Advances in Integrated 3D Printed Scaffolds with 2D Nanomaterials for Bone Repair and Regeneration

by
Recent Advances in Integrated 3D Printed Scaffolds with 2D Nanomaterials for Bone Repair and Regeneration

Click the “blue text” above to follow us!Abstract Bone defects pose a significant challenge in the field of orthopedics, and their related complications continue to present numerous difficulties in clinical practice. In the biomedical field, advancements in three-dimensional (3D) printing technology have made bone tissue engineering (BTE) scaffolds a promising and effective therapeutic strategy. These … Read more

3D-Printed Biomimetic Vascular Scaffold for Sustained Release of PDGFB-LG4 Fusion Protein Promotes Bone Regeneration

by
3D-Printed Biomimetic Vascular Scaffold for Sustained Release of PDGFB-LG4 Fusion Protein Promotes Bone Regeneration

3D-Printed Biomimetic Vascular Scaffold for Sustained Release of PDGFB-LG4 Fusion Protein Promotes Bone Regeneration Advanced Science ( IF 14.3 ) Pub Date : 2025-03-27 , DOI: 10.1002/advs.202414362 Jiahua Duan, Gaofei Qian, Huikang Zhang, Feifan Wang, Qiang Tian, Dong Lei, Jianning Zhao The 3D-printed biomimetic vascular scaffold crosslinked with heparan sulfate is used for the sustained … Read more

3D Printed Scaffolds Aid in Bone Defect Repair: A Study from Shanghai Jiao Tong University in Biomaterials

by
3D Printed Scaffolds Aid in Bone Defect Repair: A Study from Shanghai Jiao Tong University in Biomaterials

Postoperative treatment of bone tumors faces numerous challenges, the most prominent of which is the high recurrence rate of tumors. This is closely related to the inability of implants to effectively reverse the polarization state of M2 macrophages and the loss of tumor phagocytosis caused by residual tumor cells. M2 macrophages play an immunosuppressive role … Read more

Professor Luo Binghong’s Team from Jinan University Publishes in ACS Nano: A Multifunctional 3D Printed Scaffold with Spatiotemporal Release of Multiple Drugs for Bone Regeneration

by
Professor Luo Binghong's Team from Jinan University Publishes in ACS Nano: A Multifunctional 3D Printed Scaffold with Spatiotemporal Release of Multiple Drugs for Bone Regeneration

Bone defects are a common and challenging issue in the medical field. The development of biomaterials with excellent bone repair capabilities and economic practicality is of significant practical importance for the clinical treatment of bone defects. In recent years, tissue-engineered scaffolds have become increasingly popular in the treatment of bone defects. Notably, the process of … Read more

Professor Luo Binghong’s Team from Jinan University Publishes in ACS Nano: Multifunctional 3D Printed Scaffolds with Spatiotemporal Drug Release Functions for Bone Regeneration

by
Professor Luo Binghong's Team from Jinan University Publishes in ACS Nano: Multifunctional 3D Printed Scaffolds with Spatiotemporal Drug Release Functions for Bone Regeneration

Bone defects are a common and challenging issue in the medical field. The development of biomaterials with excellent bone repair capabilities and cost-effectiveness is of significant practical importance for the clinical treatment of bone defects. In recent years, tissue-engineered scaffolds have become increasingly popular for the treatment of bone defects. Notably, the process of bone … Read more