The First PROTAC DAC (ABBV-787) Clinical Trial Termination: Unveiling the Truth

The First PROTAC DAC (ABBV-787) Clinical Trial Termination: Unveiling the Truth

Following a series of DAC transactions last year, interest in this area has gradually increased, leading to various discussions and reviews. Among the products in the clinical phase of DAC, AbbVie‘s product ABBV-787 frequently appears alongside ORM-5029 and ORM-6151, but unlike the latter two, ABBV-787 has never disclosed any technical details in public forums. Although … Read more

RC88 Treatment for Platinum-Resistant Ovarian Cancer with Liver/Bone/Lymph Node Metastases: A Case Report

RC88 Treatment for Platinum-Resistant Ovarian Cancer with Liver/Bone/Lymph Node Metastases: A Case Report

AI Summary The patient had platinum-resistant ovarian cancer with multiple treatment failures, presenting with liver, lymph node, and bone metastases, and conventional treatments were ineffective. After using the novel targeted drug RC88, significant shrinkage of liver metastases and hilar lymph nodes was observed, with a reduction in the extent of bone metastases, achieving partial remission. … Read more

Clinical Research Confirms DS-8201 Effectively Treats Brain Metastases from Breast Cancer

Clinical Research Confirms DS-8201 Effectively Treats Brain Metastases from Breast Cancer

Written by Wang Cong Edited by Wang Duoyu Formatted by Shui Chengwen Breast cancer has the highest incidence rate among malignant tumors in women, thus it is referred to as the “pink killer.” According to the global cancer burden data released by the International Agency for Research on Cancer (IARC) in 2020, breast cancer has … Read more

Advancements in DS-TB Short Course Treatment and CLO-FAST Study Review

Advancements in DS-TB Short Course Treatment and CLO-FAST Study Review

Follow Us By Clicking The Blue Text Above Editor’s Note: In recent years, exploring shorter and more effective drug combinations for treating drug-sensitive tuberculosis (DS-TB) has become a significant trend in tuberculosis research, aimed at reducing adverse reactions, enhancing treatment adherence, and improving treatment efficiency and resource utilization. Previous studies such as Study 31/A5349, SHINE, … Read more