Evaluation of Reproductive Toxicity of Special Drugs: Do ADC Payloads Cause Teratogenicity, and Can Gene Therapy Vectors Integrate?
Dear non-clinical colleagues, following our previous discussion on the reproductive and developmental toxicity of traditional drugs, this time we will briefly discuss how to evaluate “special drugs” — “Which components of ADCs, such as antibodies, linkers, or payloads, need to be assessed for reproductive toxicity?” “Will gene therapy viral vectors integrate into germ cells, and … Read more
