immunogenicity

From ADC to DAC: Tackling the ‘Undruggable’ Lifeline? (Data Updated to AACR 2025)

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From ADC to DAC: Tackling the 'Undruggable' Lifeline? (Data Updated to AACR 2025)

In previous discussions about dual payloads, we mentioned that payload diversity is a crucial consideration in the future development of ADCs (ADC: Payload Evolution and Dual Payload Strategy). There are two main reasons for this: first, the existing toxin payloads have relatively singular modes of action, and treatment strategies after drug resistance need to be … Read more

Sustained Efficacy of Biologics in Psoriasis

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Sustained Efficacy of Biologics in Psoriasis

“This article is for medical professionals only” As the application of biologics in psoriasis continues to become widespread, have you had such experiences in your clinical work? “Early patients show significant clinical efficacy when using biologics, but over time, a certain proportion of patients always exhibit a decline in efficacy?” What is behind this? Let’s … Read more