RNA Fluorescent Covalent Probes

RNA Fluorescent Covalent Probes

1. Research Background Ribonucleic acid (RNA) plays a complex and central role in cellular regulation, catalysis, and signaling. Visualizing RNA during isolation and analysis, as well as in its natural cellular environment, is an important tool for analyzing its function. The ability to image populations of RNA can monitor cellular transcription, track the mobility and … Read more

Fluorogenic Covalent Probes for RNA

Fluorogenic Covalent Probes for RNA

Ribonucleic acid (RNA) plays a complex and central role in cellular regulation, catalysis, and signal transduction. Visualizing RNA in isolation and in the natural cellular environment is an important means of elucidating its functions. The ability to image populations of RNA enables monitoring of cellular transcriptional activity, tracking the migration and dynamics of various transcripts, … Read more

Precision Testing and Process Optimization in the PCB Industry

Precision Testing and Process Optimization in the PCB Industry

Technical Support: 199-6293-0018 Printed Circuit Boards (PCB) are the core interconnection carriers of electronic devices, and their manufacturing quality directly determines the stability and lifespan of the end products. With the rapid development of technologies such as 5G communication and flexible electronics, the PCB industry is exhibiting two key trends: first, increased density, with line … Read more

Literature Sharing | J. Am. Soc. Mass Spectrom | Pneumatically Assisted Microfluidic Probe for Enhanced Mass Spectrometry Imaging Performance

Literature Sharing | J. Am. Soc. Mass Spectrom | Pneumatically Assisted Microfluidic Probe for Enhanced Mass Spectrometry Imaging Performance

Hello everyone, today I would like to introduce an article published in 2025 in the Journal of the American Society for Mass Spectrometry titled “Pneumatically Assisted Microfluidic Probe for Enhanced Mass Spectrometry Imaging Performance.“ This article develops a pneumatically assisted microfluidic probe (MFP) with two microfluidic channels for nano-DESI mass spectrometry imaging of biological samples. … Read more

3D Imaging Combined with AI and Robotics for Automated Coating Inspection

3D Imaging Combined with AI and Robotics for Automated Coating Inspection

Author: Linda Wilson Figure 1: Porsche uses a machine vision system to project light patterns onto the car surface and captures the reflected light through image acquisition. Porsche is a representative of high-end luxury cars. Consumers who purchase a Porsche expect every component of the car to be flawless, including the paint finish. This is … Read more

Reasons for High Signal in Liver Lesions on DWI and ADC Sequences at b=1000

Reasons for High Signal in Liver Lesions on DWI and ADC Sequences at b=1000

Core Conclusion: At b=1000, liver lesions appear as high signals on both DWI and ADC images, which may seem contradictory theoretically, but can actually occur. This usually indicates that the signal attenuation behavior of the lesion at this specific value of b=1000 does not conform to a simple mono-exponential model, and its “high signal” nature … Read more

Diagnosis and Treatment of Primary Aldosteronism: Realities and Challenges

Diagnosis and Treatment of Primary Aldosteronism: Realities and Challenges

CK Note: The diagnosis and treatment of primary aldosteronism have formed a system, but the relatively complex processes and controversial results have left many endocrinologists confused. Primary aldosteronism also faces many challenges, mainly due to the high prevalence that exceeds previous understandings and the simplification of processes and methods; all of these require evidence. Current … Read more

Ultrasound Imaging of Intrahepatic Cholangiocarcinoma

Ultrasound Imaging of Intrahepatic Cholangiocarcinoma

The exact cause of intrahepatic cholangiocarcinoma (ICC) remains unclear. Well-known risk factors for ICC include congenital choledochal cysts, chronic cholangitis, inflammatory bowel disease, primary sclerosing cholangitis, parasitic infections, chemical carcinogens (such as thorium dioxide and nitrosamines), genetic factors, biliary cirrhosis, cholelithiasis, alcoholic liver disease, and non-specific liver cirrhosis. Recently, studies have found a close association … Read more

Cholangiocarcinoma: Insights and Clinical Perspectives

Cholangiocarcinoma: Insights and Clinical Perspectives

Source: Abdominal Medical Imaging Forum Cholangiocarcinoma Intrahepatic cholangiocarcinoma (ICC) is a type of malignant tumor composed of cells similar to bile ducts. Intrahepatic (or peripheral) cholangiocarcinoma (ICC) originates from any part of the intrahepatic bile duct epithelium, such as the large intrahepatic bile duct (segmental and regional ducts and their small branches), and the intrahepatic … Read more

Imaging Diagnosis of Intrahepatic Cholangiocarcinoma

Imaging Diagnosis of Intrahepatic Cholangiocarcinoma

Click the “Chinese Journal of Practical Surgery” above to subscribe! Professor Zhou Weiping [Cite This Article] Gu Fangming, Zhou Weiping. Imaging Diagnosis of Intrahepatic Cholangiocarcinoma [J]. Chinese Journal of Practical Surgery, 2020, 40(6): 738-740. Imaging Diagnosis of Intrahepatic Cholangiocarcinoma Gu Fangming, Zhou Weiping Chinese Journal of Practical Surgery, 2020, 40(6): 738-740 Abstract The rapid development … Read more