CK Note: The diagnosis and treatment of primary aldosteronism have formed a system, but the relatively complex processes and controversial results have left many endocrinologists confused. Primary aldosteronism also faces many challenges, mainly due to the high prevalence that exceeds previous understandings and the simplification of processes and methods; all of these require evidence. Current … Read more
👆Click the image to learn for free👆 What is the Insulin and C-Peptide Release Test? The insulin and C-peptide release test is a quantitative oral glucose (or steamed bun meal) test that raises blood sugar levels, stimulating the insulin β-cells to release insulin and C-peptide. By measuring the plasma insulin and C-peptide levels and their … Read more
Diabetes patients, especially those diagnosed for the first time, often need to check their pancreatic function through blood tests. The main methods for checking pancreatic function are the insulin and C-peptide release tests, which are very important for diagnosing diabetes, determining its type and prognosis, and guiding treatment. In this issue, we will discuss how … Read more
C-peptide is a secretion product of pancreatic β-cells, and it shares a common precursor with insulin—proinsulin. One molecule of proinsulin, under specific conditions, splits into one molecule of insulin and one molecule of C-peptide; therefore, theoretically, C-peptide and insulin are secreted in equal amounts. The physiological functions of free C-peptide in the blood are not … Read more
Guideline Consensus l 2024 Severe Primary IGF1 Deficiency (SPIGFD) Challenges in Diagnosis and Treatment: An International Stakeholder Perspective Compiled/Translated by Chen Kang Background Severe Primary Insulin-like Growth Factor-I (IGF-I) Deficiency (SPIGFD) is a rare growth disorder characterized by short stature (standard deviation score [SDS] ≤ 3.0), low circulating IGF-I (SDS ≤ 3.0) levels, and normal … Read more