cholangiocarcinoma

Ultrasound Imaging of Intrahepatic Cholangiocarcinoma

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Ultrasound Imaging of Intrahepatic Cholangiocarcinoma

The exact cause of intrahepatic cholangiocarcinoma (ICC) remains unclear. Well-known risk factors for ICC include congenital choledochal cysts, chronic cholangitis, inflammatory bowel disease, primary sclerosing cholangitis, parasitic infections, chemical carcinogens (such as thorium dioxide and nitrosamines), genetic factors, biliary cirrhosis, cholelithiasis, alcoholic liver disease, and non-specific liver cirrhosis. Recently, studies have found a close association … Read more

Summary of Immunohistochemical Markers for Liver Cancer

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Summary of Immunohistochemical Markers for Liver Cancer

In 2020, over 410,000 new cases of liver cancer were reported in China, with more than 390,000 deaths due to liver cancer, bringing the death toll close to the number of new cases. This means that for every 11 newly diagnosed cancer patients, 1 has liver cancer, and almost 1 in 8 patients who die … Read more

Interpretation of the 2022 CSCO Guidelines for Cholangiocarcinoma

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Interpretation of the 2022 CSCO Guidelines for Cholangiocarcinoma

Patients with cholangiocarcinoma (BTC) have a very poor prognosis. In recent years, both the incidence and mortality rates have shown a continuous upward trend. BTC mainly includes gallbladder cancer (GBC) and cholangiocarcinoma (CCA), which can be broadly divided into two subtypes: intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC). It is well known that clarifying the … Read more

Cholangiocarcinoma: Insights and Clinical Perspectives

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Cholangiocarcinoma: Insights and Clinical Perspectives

Source: Abdominal Medical Imaging Forum Cholangiocarcinoma Intrahepatic cholangiocarcinoma (ICC) is a type of malignant tumor composed of cells similar to bile ducts. Intrahepatic (or peripheral) cholangiocarcinoma (ICC) originates from any part of the intrahepatic bile duct epithelium, such as the large intrahepatic bile duct (segmental and regional ducts and their small branches), and the intrahepatic … Read more

Suggestions for Redefining, Classifying, and Naming ICC

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Suggestions for Redefining, Classifying, and Naming ICC

Author: Chen Minshan, Zhou Zhongguo, Xu Li, Zhang Yaojun, Lin Ximeng Source: Chinese Journal of Digestive Surgery, 2021, 20(12) Abstract Currently, there is controversy regarding the definition, classification, and Chinese naming of ICC (intrahepatic cholangiocarcinoma). It is unclear whether ICC belongs to liver cancer or bile duct cancer, and the terms “intrahepatic bile duct cancer” … Read more

How to Treat Advanced Cholangiocarcinoma in the Targeted Therapy Era?

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How to Treat Advanced Cholangiocarcinoma in the Targeted Therapy Era?

Primary liver cancer is a common malignant tumor in China, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and mixed hepatocellular carcinoma-cholangiocarcinoma (cHCC-CCA), with HCC accounting for 75% to 85% and ICC for 10% to 15%[1, 2]. Although the incidence of cholangiocarcinoma is low, its malignancy is very high, with most patients diagnosed at an advanced … Read more

Mechanisms And Clinical Translation Of Intrahepatic Cholangiocarcinoma In The Era Of Precision Medicine

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Mechanisms And Clinical Translation Of Intrahepatic Cholangiocarcinoma In The Era Of Precision Medicine

1Overview Of Intrahepatic Cholangiocarcinoma (ICC) Cholangiocarcinoma can be classified based on its anatomical location into ICC, perihilar cholangiocarcinoma, and distal cholangiocarcinoma[1]. ICC has a high incidence in East and Southeast Asian countries, with the highest incidence in Thailand, followed by China[2]. Studies[3] indicate that in recent years, the incidence and mortality rates of ICC have … Read more

Comprehensive Review of Current Advances in Intrahepatic Cholangiocarcinoma Treatment

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Comprehensive Review of Current Advances in Intrahepatic Cholangiocarcinoma Treatment

Intrahepatic cholangiocarcinoma (ICC) is a lethal malignant tumor, with an incidence rate ranking second among primary liver cancers. In the past decade, the incidence of this disease has increased by 140%. ICC accounts for 20% of all liver malignancies, and 3% of all gastrointestinal malignancies. The disease typically develops against a background of chronic inflammation, … Read more

Advances in Diagnosis and Treatment of Intrahepatic Cholangiocarcinoma

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Advances in Diagnosis and Treatment of Intrahepatic Cholangiocarcinoma

Abstract: Intrahepatic cholangiocarcinoma (ICC) is a relatively rare type of primary liver cancer, with an increasing incidence in recent years. Due to its insidious onset and atypical clinical symptoms, most patients are diagnosed at an advanced stage of the disease, making timely diagnosis and treatment crucial. The standard treatment for early-stage ICC patients is radical … Read more