Immunohistochemistry Guide: Significance of 57 Common Clinical Indicators

Micro Diagnosis Network WeChat ID: ivdcom New Media in Laboratory Medicine (www.weivd.com) What Is the Difference Between IHC and ICC? The principle of immunohistochemistry (IHC) has been known since the 1930s, but the first IHC research results were not officially published until 1942. This is regarded as a milestone in immunofluorescence technology. Albert Coons from … Read more

Cholangiocarcinoma: Insights and Clinical Perspectives

Cholangiocarcinoma: Insights and Clinical Perspectives

Source: Abdominal Medical Imaging Forum Cholangiocarcinoma Intrahepatic cholangiocarcinoma (ICC) is a type of malignant tumor composed of cells similar to bile ducts. Intrahepatic (or peripheral) cholangiocarcinoma (ICC) originates from any part of the intrahepatic bile duct epithelium, such as the large intrahepatic bile duct (segmental and regional ducts and their small branches), and the intrahepatic … Read more

Differences Between IHC and ICC: 57 Clinical Immunohistochemistry Indicators

Differences Between IHC and ICC: 57 Clinical Immunohistochemistry Indicators

What Are the Differences Between IHC and ICC? In the 1930s, the principle of Immunohistochemistry (IHC) was already known, but it wasn’t until 1942 that the first IHC research results were officially published, marking a milestone in immunofluorescence technology. Albert Coons from Harvard Medical School published an article in the Journal of Immunology, using FITC-labeled … Read more

Diagnosis and Staging of Primary Liver Cancer

Diagnosis and Staging of Primary Liver Cancer

Primary liver cancer mainly includes three different pathological types: hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and combined hepatocellular and cholangiocarcinoma (cHCC-CCA). There are significant differences among these three in terms of pathogenesis, biological behavior, histopathology, treatment methods, and prognosis. HCC accounts for 75%~85%, while ICC accounts for 10%~15%. In this article, “liver cancer” refers only … Read more

Understanding Diffuse Large B-Cell Lymphoma

Diffuse Large B-Cell Lymphoma: Composed of centroblastic (non-cleaved), B immunoblastic, and anaplastic large B-cell lymphomas classified by Kiel. Under the microscope: a relatively uniform morphology of large cells arranged diffusely can be seen. The cell morphology is diverse, resembling centroblasts, immunoblasts, and may also include multinucleated tumor cells with anaplastic features. Incidence Rate Diffuse large … Read more