Electrocatalytic Decarboxylation Csp3–N Coupling: Baran Team’s Excellent Preparation of Aryl N-Tert-alkyl Derivatives

Electrocatalytic Decarboxylation Csp3–N Coupling: Baran Team's Excellent Preparation of Aryl N-Tert-alkyl Derivatives

Phil S. Baran and his team have pioneered many astonishing electrocatalytic reactions with extraordinary creativity and foresight, which not only provide unprecedented green and efficient chemical synthesis but also offer scientists more elegant and sophisticated tools. His research has injected new vitality into the field of electrocatalysis, shining like a dazzling light, leading the chemistry … Read more

Protection of Amines with Boc Group

Protection of Amines with Boc Group

Free amines easily react with NaOH or NaHCO3 under alkaline conditions controlled by a mixture of dioxane and water to produce N-tert-butoxycarbonylated amines via reaction with Boc2O. This is one of the commonly used methods for introducing Boc, which has the advantage of producing minimal interfering by-products that are easy to remove. For some nucleophilic … Read more

New Stable Aryl Boronic Esters on Silica Gel with Higher Suzuki-Miyaura Reaction Activity!

New Stable Aryl Boronic Esters on Silica Gel with Higher Suzuki-Miyaura Reaction Activity!

Due to WeChat’s changes to subscription account push rules, many friends cannot quickly find us, but we are actually pushing every day!You can set Organic Synthesis as a star (click the upper right “…” to set it as a star), so you can quickly find us in the WeChat subscription account and check the daily … Read more