Common Reagent – PhI(OAc)2

Common Reagent - PhI(OAc)2

Name: (Diacetoxyiodo)benzene, (二乙酰氧基碘)苯 Formula: C10H11IO4 Molecular Weight: 322.10 CAS Registration Number: [3240-34-4] Abbreviations and Aliases: DIB, Iodobenzene Diacetate Physical Properties: mp 163~165 °C, soluble in most organic solvents. Commonly used in MeOH, MeCN, and AcOH solvents. Preparation and Commercial Availability: The commercial reagent is a white solid, available from foreign reagent companies. It can be … Read more

Preparation of Amines via Amide Reduction

Preparation of Amines via Amide Reduction

The reduction of amides is also a commonly used method for synthesizing amines, often employed for the monoalkylation of primary amines. The most common method for reducing amides to amines is through LAH under heated reflux. However, when sensitive functional groups are present within the molecule, such as halogens (especially bromine and iodine) on an … Read more