Corey-Bakshi-Shibata Reduction Reaction
The Corey–Bakshi–Shibata (CBS) reagent is a chiral catalyst prepared from proline. Also known as Corey boron-containing oxazolidine, it can be used with boranes for enantioselective reduction of ketones, imides, and imines, and can also serve as a Lewis acid to catalyze asymmetric Diels–Alder reactions and [3 + 2] cycloadditions. This catalyst is easy to prepare, … Read more