microfluidics

When Stem Cells Meet 3D Printing! Biofabrication: Microfluidic Bioprinting Technology Successfully ‘Prints’ Functional Kidney Organoids Responsive to Drugs

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When Stem Cells Meet 3D Printing! Biofabrication: Microfluidic Bioprinting Technology Successfully 'Prints' Functional Kidney Organoids Responsive to Drugs

Globally, chronic kidney disease (CKD) is becoming an increasingly severe health threat—statistics show that it affects about 10% of the population and ranks among the top ten causes of death in low- and middle-income countries. When the condition progresses to end-stage renal disease (ESRD), patients often rely on dialysis or kidney transplantation to sustain life, … Read more

Principles of POCT Technology | Chemiluminescence, Biosensors, Microfluidics, Immunochromatography…

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Principles of POCT Technology | Chemiluminescence, Biosensors, Microfluidics, Immunochromatography...

01 Dry Chemical Analysis Technology Dry chemical technology is compared to traditional wet chemical technology, where the liquid present in the sample serves as the reaction medium. The components to be measured react directly with dry reagents fixed on a carrier, allowing for qualitative observation or instrument detection (semi-quantitative) for chemical analysis. Single-layer Test Paper … Read more

A Novel Label-Free Method for High-Throughput Single-Cell Analysis Integrating Computer Vision and Microfluidics

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A Novel Label-Free Method for High-Throughput Single-Cell Analysis Integrating Computer Vision and Microfluidics

Hello everyone, today I would like to share a paper published in 2023 in Microsystems & Nanoengineering, titled “Computer vision meets microfluidics: a label-free method for high-throughput cell analysis”. This study reviews the integration of microfluidic chips with computer vision, which has great potential in the analysis of single-cell imaging data. A key advantage of … Read more

ACS Nano: A Fully Integrated Wearable Biomimetic Microfluidic Wound Tracker for In Situ Dynamic Monitoring of Wound Exudate Oxygen

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ACS Nano: A Fully Integrated Wearable Biomimetic Microfluidic Wound Tracker for In Situ Dynamic Monitoring of Wound Exudate Oxygen

Wearable wound exudate sensors hold great promise for dynamic measurements of valuable biomarkers. However, existing sensors fail to achieve fully integrated, skin-adhered, and dynamic detection of raw wound exudate oxygen (O2), which is closely related to wound conditions and is crucial for wound healing. Here, we report a fully integrated wearable biomimetic microfluidic wound tracker … Read more

Revolution of 3D Printing Technology in Glass Manufacturing: From Traditional Craft to Modern Marvels

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Revolution of 3D Printing Technology in Glass Manufacturing: From Traditional Craft to Modern Marvels

Glass, as one of the oldest industrial materials used by humans, has undergone an evolution in its manufacturing process over thousands of years, transitioning from blowing, casting to float glass. However, traditional methods face bottlenecks in producing complex structures and functional doping. The emergence of 3D printing technology has opened a new era for glass … Read more

One-Step Formation Method of Sperm-Like Structure Microrobots for Drug Delivery

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One-Step Formation Method of Sperm-Like Structure Microrobots for Drug Delivery

Sperm-Like Microrobots have broad application prospects in biomedicine, especially in precise drug delivery and minimally invasive surgery. However, traditional microrobots face challenges such as complex manufacturing processes, high material requirements, and poor environmental adaptability. Professor Shen Yajing’s research team at the Hong Kong University of Science and Technology proposed a vortex turbulence-assisted microfluidic platform (VTAM) … Read more

CellASIC® ONIX2: A New Platform for Live Cell Dynamic Cultivation and Analysis

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CellASIC® ONIX2: A New Platform for Live Cell Dynamic Cultivation and Analysis

Live cell in vitro functional studies play a crucial role in basic biology, drug mechanism research, and disease control model establishment. The microenvironment in which cells reside affects their health status and phenotype. Therefore, breaking through the limitations of traditional static and large-space live cell culture methods under in vitro conditions by establishing a more … Read more

Opto-Fluidically Multiplexed Assembly and Micro-Robotics

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Opto-Fluidically Multiplexed Assembly and Micro-Robotics

Banner Promotion Written by | Zhao Yixin Abstract Recently, Moritz Kreysing and others from the Karlsruhe Institute of Technology in Germany demonstrated that laser-induced local flow fields can be iteratively used for the relative positioning of multiple micro-particles. The researchers showed that multiplexing stimulated by temperatures below the thermal diffusion limit can accelerate the precise … Read more

Microfluidic Isolation and Enrichment of Nanoparticles

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Microfluidic Isolation and Enrichment of Nanoparticles

Xie Y, Rufo J, Zhong R, Rich J, Li P, Leong KW, Huang TJ. Microfluidic Isolation and Enrichment of Nanoparticles. ACS Nano. 2020 Dec 22;14(12):16220-16240. doi: 10.1021/acsnano.0c06336. Epub 2020 Nov 30. PMID: 33252215; PMCID: PMC8164652. In recent decades, the application of nanoparticles has increased in various applications, ranging from efficient electronics to targeted drug delivery. … Read more

Tips for Designing Microfluidic Chips in Diagnostic Instruments

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Tips for Designing Microfluidic Chips in Diagnostic Instruments

Design Tips 1 Microfluidic chip Since the development of the first commercial POCT instruments in the 1990s, microfluidic technology has gained increasing favor among manufacturers due to its outstanding advantages, especially in the field of diagnostics. Microfluidics is a branch of fluid mechanics that studies the physical processes of fluid flow using fundamental control equations, … Read more