Biomarkers for ADCs: IHC and Beyond

Biomarkers for ADCs: IHC and Beyond

WCLC 2025 has numerous topics on ADCs, and in the spirit of learning, I am joining the discussion. Let’s see how ADCs are viewed in the field of lung cancer, a leading area in cancer treatment, and what research directions exist for ADCs in this domain.Biomarkers for ADCs: IHC and Beyond, presented by Dr. Sewanti … Read more

From ‘One-Size-Fits-All’ to ‘Tailored Solutions’: ADC+IO Combination Breaks the Treatment Dilemma of MIBC

From 'One-Size-Fits-All' to 'Tailored Solutions': ADC+IO Combination Breaks the Treatment Dilemma of MIBC

Key Points 1 For patients with muscle-invasive bladder cancer (MIBC) who are not suitable for cisplatin treatment, sacituzumab govitecan and pembrolizumab show promise as alternatives to radical cystectomy, with a clinical complete response rate (cCR) of 44.4%. 2 The SURE-02 trial emphasizes bladder preservation, adjusting treatment plans based on patient preferences and treatment responses, shifting … Read more

Short-Wave Infrared Semi-Cyano-6 for Cancer Activation and Non-Hairless Preclinical Imaging of Lung Metastasis

Short-Wave Infrared Semi-Cyano-6 for Cancer Activation and Non-Hairless Preclinical Imaging of Lung Metastasis

Published by Nanyang Technological University, Pu Kanyi on 2025.8.12 Recent articles by the corresponding author: Adv. Funct. Mater. | Near-infrared bioorthogonal activatable fluorescent probes for in vivo imaging of cancer immune checkpoints Research Highlights The fluorescence imaging technology in the short-wave infrared (SWIR) window allows for high-contrast visualization of deeper tissue pathological events compared to … Read more