digital microfluidics

Grayscale Photopolymerization 3D Printing Promotes the Fine Manufacturing of Functionally Graded Materials

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Grayscale Photopolymerization 3D Printing Promotes the Fine Manufacturing of Functionally Graded Materials

Click the blue text to follow us immediately This research was conducted by Guanghai Fei and his team from KU Leuven in Belgium and published in the journal Advanced Functional Materials. The article systematically reviews the current development status and application prospects of grayscale photopolymerization 3D printing technology, focusing on its potential in the preparation … Read more

Microfluidic Technology Enhances Chip Cooling Efficiency: Corintis Advances Related R&D and Manufacturing

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Microfluidic Technology Enhances Chip Cooling Efficiency: Corintis Advances Related R&D and Manufacturing

The Swiss company Corintis is dedicated to advancing a cutting-edge cooling technology based on microfluidics, which achieves efficient heat dissipation by precisely delivering water or other cooling fluids to the heat-generating core areas of chips. In a recent test conducted in collaboration with Microsoft, servers equipped with this technology achieved cooling efficiency three times that … Read more

How Organoid Chips Achieve Precise Reproduction of 0%–21% Oxygen Gradients, Revealing the Mechanisms of Hypoxic Metabolic Reprogramming in Tumors and Ischemic Diseases

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1. Overview The goal is to construct and stably maintain a spatial oxygen gradient ranging from normoxia (≈21% O₂ gas phase) to anoxia/zero oxygen (0% O₂ gas phase) on a reproducible and quantifiable organoid/tumor-on-chip platform, and to achieve real-time/periodic monitoring and biological sampling to elucidate hypoxia-induced metabolic reprogramming (such as HIF pathways, glycolysis/lactate production, mitochondrial … Read more

3D Printed Chips Empower CRISPR for Rapid On-Site Detection of Foodborne Bacteria

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3D Printed Chips Empower CRISPR for Rapid On-Site Detection of Foodborne Bacteria

Recently, Professor Ding Xiong’s team from Southeast University published significant research findings in the journal Advanced Science, successfully developing a deployable platform for the multiplex detection of foodborne bacteria. This platform ingeniously combines an enhanced CRISPR detection system with 3D printed microfluidic chips, providing a revolutionary solution for rapid food safety testing. The team’s enhanced … Read more

3D Printed Integrated Microfluidic Optogenetic Neural Probes: Combining Optical Stimulation with Drug/Virus Delivery Functions

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3D Printed Integrated Microfluidic Optogenetic Neural Probes: Combining Optical Stimulation with Drug/Virus Delivery Functions

Recently, a study by Revathi Sukesan and her team from New York University published in Scientific Reports showcased an innovative 3D printed multimodal optogenetic neural probe. This research successfully addresses the challenge of multiple surgeries required in traditional optogenetic studies by integrating optical stimulation with microfluidic drug/virus delivery functions into a single device, providing an … Read more

Main Technical Approaches of Flexible Tactile Sensors

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Main Technical Approaches of Flexible Tactile Sensors

A tactile sensing array is a tactile sensor composed of multiple tactile sensing units. Each tactile sensing unit can measure the contact force at a single point, while the tactile sensing array, by integrating multiple sensing units, has the capability to detect distributed contact forces. Currently, there are various methods to implement tactile sensing, which … Read more

Integrating Cooling Liquid into Chips: Microsoft’s Cooling Revolution and Its Road to Implementation

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Integrating Cooling Liquid into Chips: Microsoft's Cooling Revolution and Its Road to Implementation

As the AI computing power race reaches a fever pitch, chip power consumption has surged from hundreds of watts to over a thousand watts, making traditional air cooling and cold plate cooling technologies increasingly inadequate. Cooling efficiency has become a core physical bottleneck restricting breakthroughs in the industry. At this critical moment, Microsoft has dropped … Read more

A Color-Changing Hydrogel Microfluidic Pressure Sensor

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A Color-Changing Hydrogel Microfluidic Pressure Sensor

Background Accurate measurement of pressure in microfluidics is crucial for flow control, fluid characterization, and monitoring, but it faces challenges such as achieving sufficient resolution, non-invasiveness, and ease of use. Sensor Design and Mechanism Researchers from the University of Portsmouth (PSL) and Hokkaido University have designed a fully integrated multiplexed optical microfluidic pressure sensor that … Read more

Digital Microfluidic Platform for Integrated Electrochemical Sensors: Automated Extraction and Detection of Extracellular Vesicles

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Digital Microfluidic Platform for Integrated Electrochemical Sensors: Automated Extraction and Detection of Extracellular Vesicles

Extracellular vesicles (EVs) are nanometer-sized particles enveloped by phospholipids that are secreted by cells into the surrounding environment. EVs can convey various biomolecules that mediate intercellular communication and play crucial roles in physiological and pathological processes. Therefore, EVs are emerging as new biomarkers, therapeutic targets, and drug delivery vehicles for various diseases. However, the isolation … Read more