organoid chips

How Organoid Chips Achieve Precise Reproduction of 0%–21% Oxygen Gradients, Revealing the Mechanisms of Hypoxic Metabolic Reprogramming in Tumors and Ischemic Diseases

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1. Overview The goal is to construct and stably maintain a spatial oxygen gradient ranging from normoxia (≈21% O₂ gas phase) to anoxia/zero oxygen (0% O₂ gas phase) on a reproducible and quantifiable organoid/tumor-on-chip platform, and to achieve real-time/periodic monitoring and biological sampling to elucidate hypoxia-induced metabolic reprogramming (such as HIF pathways, glycolysis/lactate production, mitochondrial … Read more

Episode 32 Podcast: Organoid Chips and Hydrogels – A Comprehensive Performance Overview

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Su Zhe: Today, we are going to discuss a topic that sounds a bit hardcore: organoid chips. You might wonder, why do scientific experiments require so many complex testing methods to validate results? Actually, there is a particularly interesting analogy behind this. Gao Qing: Oh? What analogy? Su Zhe:It’s like introducing a blind date to … Read more

Bibliometric Insights into Breast Cancer Organoid Chips: Trends & Emerging Areas

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Bibliometric Insights into Breast Cancer Organoid Chips: Trends & Emerging Areas

[Yangtze Alliance Reading 365 Day 267] “Bibliometric Insights into Breast Cancer Organoid Chips: Trends & Emerging Areas“ published in “Int J Surg“Breast cancer is a highly prevalent malignant tumor among women worldwide, and its treatment faces challenges due to the diversity of genetic mutations and individual patient differences. Organoid chip technology provides new tools for … Read more