photodynamic therapy

pH-Activated Nanoplatform for Tumor Therapy

by
pH-Activated Nanoplatform for Tumor Therapy

Professor Yu Zhiqiang from Southern Medical University and Researcher Tang Longguang from Zhejiang University published a research paper titled “pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors” in the international academic journal Journal of Controlled Release (IF=11.467). Compared to traditional chemotherapy, photodynamic therapy (PDT) can effectively reduce side effects and prevent drug … Read more

Potent Covalent Organic Framework Nanophotosensitizers for Photodynamic Immunotherapy

by
Potent Covalent Organic Framework Nanophotosensitizers for Photodynamic Immunotherapy

iNature The photodynamic therapy (PDT) using oxygen-dependent type II photosensitizers is often limited by the hypoxic microenvironment of solid tumors. Type I photosensitizers generate oxygen-independent reactive oxygen species (ROS) under light irradiation, but they suffer from aggregation-caused quenching (ACQ) and low ROS generation efficiency. On December 19, 2024, the team led by Ge Zhishen from … Read more

Enhancing AIEgen Fluorescence Efficiency via Anion-π+ Interaction

by
Enhancing AIEgen Fluorescence Efficiency via Anion-π+ Interaction

Cancer poses a severe threat to human health, making the development of photosensitizers with both diagnostic and therapeutic functions significant in combating cancer. Thanks to the excellent aggregation-induced emission (AIE) efficiency and reactive oxygen species (ROS) generation capability, AIE technology shows tremendous advantages in fluorescence imaging-guided photodynamic cancer therapy (integrated diagnosis and treatment). However, the … Read more

Enhancing Fluorescence Efficiency and Reactive Oxygen Species Generation through Anion-π+ Interaction and Crowded Conformation

by
Enhancing Fluorescence Efficiency and Reactive Oxygen Species Generation through Anion-π+ Interaction and Crowded Conformation

Cancer is a terrifying public health threat with low survival rates and a global prevalence. Therefore, exploring effective diagnostic and therapeutic methods is crucial. Traditional cancer treatments, including surgery, radiotherapy, and chemotherapy, often prove to be limited in efficacy and significant in side effects. Fortunately, fluorescence imaging-guided photodynamic therapy (FLI-guided PDT) offers a non-invasive strategy … Read more