cisplatin

Systemic Treatment for Advanced Intrahepatic Cholangiocarcinoma (ICC)

by
Systemic Treatment for Advanced Intrahepatic Cholangiocarcinoma (ICC)

Intrahepatic cholangiocarcinoma (ICC) originates from the epithelial cells of the intrahepatic bile ducts. Among primary liver malignancies, the incidence of ICC is second only to hepatocellular carcinoma, accounting for 10% to 15% of primary liver cancer. Recommended Suggestions 1) It is recommended to use a combination regimen of gemcitabine and platinum-based drugs, and if conditions … Read more

Platinum(IV)-Backboned Polymer Prodrug-Functionalized Manganese Oxide Nanoparticles for Enhanced Lung Cancer Chemoimmunotherapy

by
Platinum(IV)-Backboned Polymer Prodrug-Functionalized Manganese Oxide Nanoparticles for Enhanced Lung Cancer Chemoimmunotherapy

iNature The stimulator of interferon genes (STING) pathway shows great potential in reshaping the immunosuppressive tumor microenvironment and initiating anti-tumor immunity. However, effectively activating STING while avoiding toxic side effects from systemic administration remains challenging. On January 7, 2025, a communication from Li Weimin’s team at Sichuan University was published online in ACS Nano titled … Read more