Insights on Learning ADC (250621)

Insights on Learning ADC (250621)

This week, I studied the first half of Chapter 3, which mainly discusses electrical principles. This chapter starts with the most basic and easily understandable component, the resistor, and then introduces commonly used concepts such as voltage and temperature coefficient. It then discusses electromigration, a phenomenon that needs to be avoided in design to prevent … Read more

High-Level Capacitor Calibration for ADCs

High-Level Capacitor Calibration for ADCs

“A 12-bit 104-MS/s SAR ADC in 28nm CMOS for Digitally-Assisted Wireless Transmitters”The calibration method introduced here utilizes low-level capacitors to calibrate high-level capacitors, as the absolute mismatch of high-level capacitors is greater, which in turn has a larger impact on DNL and INL. Calibrating high-level capacitors can effectively improve the dynamic range of the ADC.As … Read more

ADC Innovation Drugs: The Golden Inflection Point, Can We Seize It?

ADC Innovation Drugs: The Golden Inflection Point, Can We Seize It?

Recently, the WeChat update has disrupted the release schedule, causing many readers to miss article updates. Please set “Fengkou Research” as a star ⭐ so we can move forward together and see each other every day! ADC, a potential new star in the field of innovative drugs In the vast starry sky of innovative drugs, … Read more

New Pathway for ADCs – Dual Payload ADCs

New Pathway for ADCs - Dual Payload ADCs

Currently, all marketed ADC drug molecules use a single small molecule toxin as the effective payload, but challenges such as drug resistance and limited therapeutic effects still exist. Therefore, clinical chemotherapy regimens often employ combinations of multiple drugs for combination therapy. Considering the clinical efficacy of combination chemotherapy, ADC drugs with two or more effective … Read more

The Arrival of Quadruple Antibody-Drug Conjugates (ADCs)

The Arrival of Quadruple Antibody-Drug Conjugates (ADCs)

The development of next-generation ADC drugs has gradually shifted towards the development of new toxins and linkers as foundational technologies. Multi-antibody or multi-toxin approaches have become a new trend. Following Araris and Puzhong’s advancements in tri-toxin and hexatozin,Aarvik has now introduced quadruple antibody-drug conjugates (ADCs). Aarvik may not have a prominent reputation in the ADC … Read more

The Development History of ADC Over 40 Years (Part 2)

The Development History of ADC Over 40 Years (Part 2)

Key Components and Mechanisms of ADC Stability The instability of linkers in the bloodstream (also known as premature payload release) is a major factor limiting the therapeutic index of ADCs. Stabilization technologies are strategies to improve the therapeutic window. If the drug cannot be linked to the ADC, it cannot be delivered directly to tumor … Read more

Bus Overview

Bus Overview

Learning notes for the software examination, all experts are welcome to provide corrections.<span>June 21, 2025</span> 1 Introduction A bus refers to a common data channel for transmitting information between devices in a computer. The classification of buses is as follows: Internal Bus: The bus that connects the arithmetic unit, controller, and various register components within … Read more

RT-Thread SPI Chained Transmission Illegal Access? Unveiling the Fatal Trap!

RT-Thread SPI Chained Transmission Illegal Access? Unveiling the Fatal Trap!

1. Introduction In discussions with developers using the Xianji RT-Thread BSP, it was found that the SPI device driver occasionally encounters illegal access exceptions in polling mode (as shown in the figure). Problem reproduction scenario:: 1. The developer only needs to transmit a single message once but did not explicitly initialize the struct rt_spi_message’s next … Read more

Understanding the SPI Mechanism in Java

Understanding the SPI Mechanism in Java

The SPI (Service Provider Interface) is a built-in service provider discovery mechanism in JDK.It can find service implementations for a specific interface.Demo: public class TestSpi { public static void main(String[] args) throws InstantiationException, IllegalAccessException { ServiceLoader<SpiInterface> load = ServiceLoader.load(SpiInterface.class); Iterator<SpiInterface> iterator = load.iterator(); if (iterator.hasNext()) { SpiInterface next = iterator.next(); next.spiInterFaceMethod("hello"); } } } Interface: … Read more

Research and Design of Digital Recognition Algorithm for Electronic Blood Pressure Monitors Based on Computer Vision

Research and Design of Digital Recognition Algorithm for Electronic Blood Pressure Monitors Based on Computer Vision

Click the blue text to follow us READINGAbstract In response to the recent regulations issued by the National Medical Products Administration, which will comprehensively ban the use of mercury sphygmomanometers, and the current situation where electronic blood pressure monitors need regular calibration and quality testing, this paper proposes an intelligent algorithm based on digital image … Read more