Exploring Tiny Robots Within the Human Body

Exploring Tiny Robots Within the Human Body

In the 1966 American science fiction film “Fantastic Voyage,” several American doctors shrink a submarine to a size smaller than a red blood cell and send it through blood vessels into the brain to clear a clot blocking the brain, ultimately saving a scientist’s life. From this film, we can see that the concept of … Read more

The Application of Slime Robots in the Medical Field

The Application of Slime Robots in the Medical Field

In today’s rapidly advancing technology, robotics has gradually permeated every aspect of our lives, especially in the medical field, where the application of robotic technology is becoming increasingly widespread and important. Traditional medical robots, such as surgical robots, have demonstrated exceptional performance in minimally invasive surgeries and precise excisions. However, with continuous technological advancements and … Read more

Transforming Cancer-Associated Fibroblast Barriers for Tumor Treatment

Transforming Cancer-Associated Fibroblast Barriers for Tumor Treatment

The cancer-associated fibroblast (CAF) barrier in pancreatic ductal adenocarcinoma (PDAC) significantly restricts clinical prognosis. The main obstacles in PDAC treatment include limited immune cell and drug penetration, as well as an immunosuppressive microenvironment. Based on this, Yongjun Liu and Na Zhang from Shandong University reported a “shooting fish in a barrel” strategy by preparing a … Read more

Multicomponent Herbal Small Molecule Hydrogels for TBI Treatment

Multicomponent Herbal Small Molecule Hydrogels for TBI Treatment

iNature Self-assembling hydrogels for mechanical support and drug delivery have been widely studied in the context of traumatic brain injury (TBI). However, most self-assembling hydrogels rely on polymer carriers or the introduction of exogenous inactive substances, often raising biosafety concerns and making clinical translation difficult. On October 9, 2024, a research paper titled “Small Molecule … Read more

Understanding The Mechanism of Immune Response Triggered by Different Lipid Components in Lipid Nanoparticles (LNP)

Understanding The Mechanism of Immune Response Triggered by Different Lipid Components in Lipid Nanoparticles (LNP)

Note: This article does not constitute any investment opinion or advice, and should be based on official/company announcements; it is only intended for the introduction of medical and health-related drugs and does not represent treatment recommendations (if involved), nor does it represent the position of Yao Hai Biotechnology. Any reproduction of this article requires authorization. … Read more

Laser and Gold Nanoparticles: Breaking the Blood-Brain Barrier for Faster Drug Delivery

Laser and Gold Nanoparticles: Breaking the Blood-Brain Barrier for Faster Drug Delivery

Written by | Xiao Xia Edited by | Wang Duoyu Formatted by | Shui Chengwen Blood-Brain Barrier (BBB) is the barrier formed between the plasma and brain cells by the walls of brain capillaries and glial cells, and the barrier formed between plasma and cerebrospinal fluid by the choroid plexus, only allowing specific types of … Read more

Repurposing Cationic Amphiphilic Drugs for mRNA Delivery

Repurposing Cationic Amphiphilic Drugs for mRNA Delivery

Recently, Professor Koen Raemdonck’s team at the University of Ghent, Belgium published a research paper titled “A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs” in The Journal of Controlled Release, Volume 350, 2022. The team utilized various cationic amphiphilic drugs as structural and functional components to prepare lipid nanoparticles (LNPs) … Read more

Quantitative Testing of Nebulizer Delivery Efficiency Under Different Breathing Patterns

Quantitative Testing of Nebulizer Delivery Efficiency Under Different Breathing Patterns

Abstract Background:A nebulizer is a medical device that delivers aerosolized medication directly to the lungs to treat various respiratory diseases. However, breathing patterns, respiratory rates, airway diameters, and the amount of medication delivered by the nebulizer may be related to respiratory diseases. Methods:In this study, we developed a breathing simulator consisting of an airway model, … Read more

Don’t Underestimate This Micro Robot, It Can Do Any Pose!

Don't Underestimate This Micro Robot, It Can Do Any Pose!

Have you heard of “head transplant surgery”? I saw this news a while ago, but when I searched online, the world’s first head transplant surgery was actually performed back in 2016… Modern medicine always gives us the illusion – Afraid of the pain of injections? Doctors can use needle-free injectors to give you shots; Need … Read more

Bacterial Microrobots for Targeted Drug Delivery to Tumors

Bacterial Microrobots for Targeted Drug Delivery to Tumors

In a new study, researchers from the Max Planck Institute for Intelligent Systems in Germany combined robotics with biology, equipping Escherichia coli with artificial components to construct biohybrid microrobots. First, they attached several nanoliposomes to each E. coli, which encapsulated indocyanine green (ICG) that melts when exposed to near-infrared light. Moving inward, these nanoliposomes contain … Read more