1. Introduction Fans often complain to me about why I always use Baidu Cloud to distribute materials. After downloading them, they have to upload them to the server again for analysis. In fact, there is no need for such a roundabout process; Baidu Cloud also has a Linux version. Using the Python package bypy to … Read more
It is very important for bioinformatics learners to master Linux because: First, Linux supports large files (such as genomic data) and large-scale data processing better than other operating systems; Second, Linux provides a powerful command line interface that can efficiently handle massive data (for example, batch processing 1000 genomic files), automating and reproducing analysis workflows, … Read more
Good morning, everyone. Today we continue our discussion on “Essential Linux Skills for Bioinformatics Analysis“ In the world of bioinformatics analysis, we deal with various mysterious data files every day: FASTQ files hide the secrets of DNA sequences, GFF annotation files record the location information of genes, and VCF files store the results of variant … Read more
Databases are a major component of bioinformatics, with various databases covering almost all fields of life sciences. Nucleic acid sequence databases include GenBank, EMBL, DDB, etc.; protein sequence databases include SWISS-PROT, PIR, OWL, NRL3D, TrEMBL, etc.; protein fragment databases include PROSITE, BLOCKS, PRINTS, etc.; three-dimensional structure databases include PDB, NDB, BioMagResBank, CCSD, etc.; databases related … Read more
Click the arrow to follow us on the “In Vitro Diagnostic POCT Forum”! Molecular diagnosis is a method and process that uses DNA, RNA, or protein molecules as diagnostic materials to specifically diagnose the state of the human body or diseases by examining the presence, defects, or abnormal expression of endogenous genes or exogenous (pathogen) … Read more
1. Training Objectives: This course is suitable for students in grades four to seven who have completed Scratch programming or have a basic knowledge of Python, starting from zero knowledge. The focus is on training students’ thinking abilities and practical skills in analyzing and solving problems, laying a foundation for deeper and broader knowledge learning … Read more
1. Introduction to MultiQC The advancement of NGS technology has spawned new experimental designs, analysis types, and the generation of high-throughput sequencing data. For the quality assessment of these data, evaluating the results at each step of the analysis is crucial for ensuring the reliability of subsequent results. Many bioinformatics tools can generate evaluation results … Read more
Introduction Protein complexes are key molecules that perform complex functions within cells. Understanding the structure of these complexes not only helps to reveal their functional mechanisms but also provides new ideas for drug development and disease treatment. However, with the deepening of research, the number and complexity of protein complexes have increased dramatically, and how … Read more
Introduction Continuing from the previous lecture (Linux | 19. File Search: find, locate, which), the which command cannot locate the ll command because it is not an executable file formally listed in the $PATH, but rather an alias. For detailed information about the alias command alias, you can refer to the video in this lecture. … Read more
Introduction There are two main reasons for introducing the concepts of users and groups:1. When providing bioinformatics servers (Why use servers for bioinformatics analysis?), some students ask: Is my data stored on the server secure? Will someone be able to view and steal my data? This question can be answered as follows: Linux has a … Read more