PCR

Comprehensive Overview of 7 Types of Molecular Diagnostic Instruments and Products

by
Comprehensive Overview of 7 Types of Molecular Diagnostic Instruments and Products

Source: IVD Practitioner Network Author: Suo Yan Molecular diagnostics of genetic nucleic acids is driven by the needs of modern life sciences, utilizing various advanced manufacturing and instrumentation technologies to develop detection instruments. It combines various testing techniques, analytical techniques, and scientific principles from other foundational disciplines to qualitatively and quantitatively observe, compare, analyze, and … Read more

Key Points of DNA Methylation (BSP MSP) Technology

by
Key Points of DNA Methylation (BSP MSP) Technology

DNA methylation is one of the earliest discovered forms of gene epigenetic modification. In eukaryotes, methylation occurs only at cytosine, where DNA methyltransferases (DNMTs) convert the 5′ end cytosine of CpG dinucleotides to 5′-methylcytosine. Numerous studies have shown that DNA methylation can induce changes in chromatin structure, DNA conformation, DNA stability, and the interaction patterns … Read more

Bisulfite Sequencing PCR (BSP) Method

by
Bisulfite Sequencing PCR (BSP) Method

In a previous article, we discussed the prediction of CpG islands. Once a CpG island is identified, it is necessary to detect the methylation status of the corresponding region. There are various methods to detect methylation status, but the currently recognized gold standard is the bisulfite sequencing PCR (BSP). BSP Principle Genomic DNA is treated … Read more

7 Open Source Hardware Projects to Combat COVID-19

by
7 Open Source Hardware Projects to Combat COVID-19

Open source hardware solutions can contribute to combating the spread and suffering caused by the novel coronavirus. — Harris Kenny The open source hardware movement has long advocated for the importance of the right to repair, fully owning the technology purchased, and being able to recombine and replicate parts like music. Therefore, during this challenging … Read more