A Comprehensive Guide to Non-Clinical Pharmacology and Toxicology Assessment of ADCs

A Comprehensive Guide to Non-Clinical Pharmacology and Toxicology Assessment of ADCs

Recently, ADC (Antibody-Drug Conjugate) conferences have been held one after another, with major biotech companies competing to report their ADC pipelines. It is expected that 2024 will still be the main venue for ADCs. Developing an entry-level ADC seems not difficult, but evaluating the pharmacology and toxicology in the preclinical stage has become a top … Read more

What Magic Do ADCs and RDCs Hold?

What Magic Do ADCs and RDCs Hold?

ADCs (Antibody-Drug Conjugates) and RDCs (Radionuclide Conjugates) are innovative drugs that have gained significant attention in recent years, demonstrating enormous potential in the field of oncology. They are referred to as the “magic bullets” of tumor-targeted therapy because they enable precise treatment while avoiding damage to normal cells. ADC drugs link antibodies with known effective … Read more

Physicochemical Analysis and Structural Characterization of Antibody-Drug Conjugates (ADCs)

Physicochemical Analysis and Structural Characterization of Antibody-Drug Conjugates (ADCs)

Preface Preface Author Cloud Assistant Antibody-drug conjugates (ADCs) are a class of emerging drugs that combine the advantages of both antibodies and small molecule toxins. Compared to traditional cytotoxic drugs, ADCs have the advantages of strong targeting and fewer side effects, making them promising in the field of tumor therapy. To date, 11 ADC drugs … Read more