Single-Molecule Reactor Based on the Excluded Volume Effect of Bottlebrush Polymers

Hello everyone, today I would like to share a recently published article in J. Am. Chem. Soc. titled Single-Molecule Reactor Based on the Excluded Volume Effect of Bottlebrush Polymers. The corresponding author of the article is Professor Shintaro Nakagawa from the University of Tokyo. Living organisms rely on various chemical reactions to sustain life, which … Read more

RNA-Activated CRISPR/Cas12a Nanorobots Operating in Live Cells

Abstract The active clustered regularly interspaced short palindromic repeats (CRISPR/Cas12a) system possesses cis-cleavage (targeting) and trans-cleavage (off-target) activities, which are highly useful for genome engineering and diagnostic applications. Both single-stranded and double-stranded DNA can activate crRNA−Cas12a ribonucleoprotein (RNP), enabling its cis and trans cleavage enzymatic activities. However, whether RNA can activate the CRISPR/Cas12a system and … Read more

Unlocking Chromium Decarboxylative Ligand-to-Metal Charge Transfer: Efficient and Redox-Neutral Allylation of Aldehydes Using Carboxylic Acids

Recently, Professor Alexander W. Schuppe’s team from Vanderbilt University reported in J. Am. Chem. Soc. the decarboxylative ligand-to-metal charge transfer (LMCT) reaction of photoinduced Cr (III) carboxylate complexes, applying it to the stereoselective Nozaki-Hiyama-Kishi (NHK) allylation reaction. This method directly utilizes carboxylic acids without the need for external redox reagents, achieving good yields and high … Read more

New Breakthrough in Photocatalysis! Direct Conversion of Carboxylic Acids to Radicals, Adding a New Tool for Green Chemistry, Goodbye to Heavy Metals!

Image source: J. Am. Chem. Soc.Introduction: The carboxyl radical, as a highly reactive intermediate, is expected to open unique transformation pathways for radical chemistry. However, the current methods for directly generating carboxyl radicals from carboxylic acids mostly rely on environmentally unfriendly processes, and their applications are mainly limited to decarboxylation functionalization reactions. This study proposes … Read more

The Trend of Advanced Autonomous Driving: SoC Becomes the Golden Pathway

The following is a 5000-wordhumorous analysis version of the report “The Trend of Advanced Autonomous Driving: SoC Becomes the Golden Pathway”, deconstructing the hardcore industry with jokes. Please read with caution: 1. Automotive Electronic Architecture: From “Scattered Jiangsu” to “Yangtze River Delta Integration” The report states that the automotive electronic architecture is shifting fromdistributed (ECUs … Read more

Improvement of Dynamic IR Drop Performance in SoC Chip Power Design

The design of the power grid has a direct impact on chip performance and reliability. It is essential to ensure that the power grid provides sufficient power voltage to all transistors within the cells, allowing the chip to operate normally under all possible conditions within a certain noise tolerance. However, as technology shrinks, the threshold … Read more

ARMv9/v8 Power Management Domains (Voltage Domain/Power Domain)

ver0.2 Introduction In previous articles, we briefly introduced the Power Control Framework (PCF) and understood the main functions of its core components, which revolve around two key concepts: “power domains” and “power modes”. Building on this foundation, this article will further explore the concept of granular “domains” controlled by the SCP for various agents. Modern … Read more

Allwinner Technology: Consumer Demand Rebounds, Performance Enters Growth Phase – What Are the Company’s Strengths and Weaknesses?

01. Company Overview Recently, I have been busy traveling for due diligence on chip design companies, and I would like to briefly discuss Allwinner Technology, one of the leading SoC chip manufacturers. The core founding team of Allwinner Technology originated from Zhuhai Jieli, and in September 2007, Zhang Jianhui and others jointly established Allwinner Technology … Read more

OpenHarmony SDK Compilation Issues Documentation

OpenHarmony is still immature on the RK3588, and SDK compilation often fails. This document records the issues encountered during compilation. Disallowed exec_script call camera_dump.cpp xxxx depend part xxxx need set part deps xxx info to xxxx allocating an object of abstract class type 1. Disallowed exec_script call This issue arises when the BUILD.gn in OpenHarmony … Read more

Overview of Core Stocks in the Upstream PCB Industry

As the mother of electronic products, PCBs (Printed Circuit Boards) are currently at the forefront of domestic substitution and technological breakthroughs, particularly in copper-clad laminates and high-end copper foil. In recent years, benefiting from the booming development of computing power and the new energy vehicle industry, the entire sector has entered a period of rapid … Read more