Synergizing Catalysis with Post-catalysis Pseudo-Iron Release by Building Dynamic Catalytic Active Sites in Diatomic Nanozymes for Boosting Cancer Therapy

Synergizing Catalysis with Post-catalysis Pseudo-Iron Release by Building Dynamic Catalytic Active Sites in Diatomic Nanozymes for Boosting Cancer TherapyJournal of the American Chemical Society ( IF 14.4 ) Pub Date : 2025-04-25DOI: 10.1021/jacs.5c03804Diatomic nanozymes have significant potential in tumor therapy, but their therapeutic efficacy is often limited by their low catalytic activity. Here, we propose … Read more

How Activated PKA is Reset

Hello everyone, today I am sharing an article published in JACS titled “Multiplicity of Regulatory Subunit Conformations Defines Structural Ensemble of Reset Protein Kinase A Holoenzyme.” The corresponding author is Professor Ganesh S. Anand from Pennsylvania State University, whose research focuses on using mass spectrometry tools to reveal the dynamic processes of cellular macromolecular assembly. … Read more

XiaoYao Dual-Core Battery (3): Overall Solution for Vehicle High Voltage Platform Matching + SOC Calculation

Click the aboveblue to follow our public account and set it as a star⭐, so you can see the latest content first。 The low-voltage dual-core architecture of the XiaoYao dual-core battery draws on the dual-engine redundancy design in the aviation field (such as the Boeing 787), dividing the low-voltage power supply system into two independent … Read more

Comprehensive Overview of the Polarity of Free Radical Types

Continuing from the previous article, this section will further introduce the types of free radicals.The Ohio State UniversityNagibresearch team summarized the polarities ofnitrogen-substituted carbon-centered free radicals, aryl free radicals, and aromatic compounds with multiple heteroatom substitutions, as well as nitrogen, oxygen, and sulfur-substituted aryl free radicals.The polarity of nitrogen-substituted carbon-centered free radicals is shown in … Read more

Gateland SoC Chips Empower Multiple Popular Models at the Shanghai Auto Show, Enhancing Safer and More Reliable Intelligent Driving Assistance

2025 Shanghai Auto Show Recently, the 2025 Shanghai Auto Show is in full swing. This global automotive industry event not only showcases the latest models and technology trends but also serves as a competitive arena for intelligent innovation achievements. Several popular models equipped with intelligent driving assistance systems, such as BYD’s “Heavenly Eye”, Huawei’s Wenjie, … Read more

Unveiling ARM Cortex-M Startup: From Power-On to Your main() Function

Today, let’s delve into a seemingly basic yet often overlooked topic — what exactly happens from the moment you press the reset button until your <span>main()</span> function begins execution? Overview of the Startup Process: The Journey of System Awakening Imagine your MCU as a robot just awakened. It needs to get dressed (load the stack), … Read more

Analysis of Rockchip’s 2024 Annual Report and Q1 2025 Report

Rockchip released its 2024 annual report and Q1 2025 report last night. This article mainly records the observation points.The performance is impressive, no need for further elaboration. The product matrix has taken shape, and the “top-down and bottom-up, yin-yang coordination” strategy is beginning to show its power. This annual report has changed the original eight-character … Read more