Recently, Associate Professor Zhang Wenli’s team at China Pharmaceutical University published a review titled “The Janus of Protein Corona on Nanoparticles for Tumor Targeting, Immunotherapy and Diagnosis” in Journal of Controlled Release, Volume 345, 2022, and it was selected as the Inside Back Cover article of that issue.. Figure 1. The dual-edged effect of protein … Read more
Sonodynamic therapy (SDT) is a non-invasive treatment method based on reactive oxygen species (ROS) that interacts with ultrasound (US) activated sonosensitizers and surrounding oxygen and water molecules to produce highly cytotoxic ROS and induce apoptosis. Due to its ability to penetrate deep tissues while causing minimal damage to normal cells, it has significant potential in … Read more
Source: Old Thousand and His Friends Original Author: Sun Qian The Time-of-Flight Secondary Ion Mass Spectrometer has developed into a powerful micro-surface analysis application technology. This technology can be applied in areas where traditional dynamic SIMS cannot, with the following advantages: it can synchronously detect different ions over an almost unlimited mass range; it has … Read more
The eukaryotic genome exhibits various repetitive sequences (such as centromeres, telomeres, etc.) and long gaps, which increasingly highlight the shortcomings of existing sequencing technologies. Although second-generation sequencing technologies can cheaply generate a large amount of sequencing data, their read length limitations prevent a simple and intuitive view of structural changes across the entire genome; PacBio … Read more
With the development and application of microelectronics technology, flexible thin-film transistors with characteristics such as bendability, deformability, and portability have attracted extensive research in fields such as wearable health management devices and flexible displays. Flexible thin-film transistors made of metal oxides, although they have better performance and stability compared to transistors made from carbon nanotubes … Read more
First Author: Xue Zhixin Corresponding Author: Xu Guiyin Affiliation: Donghua University Summary of Results Sodium-ion batteries (SIBs) are receiving widespread attention due to their low cost, low-temperature performance, and fast charging capabilities. The membrane is one of the essential key components of the battery, affecting the battery’s interface structure, internal resistance, capacity, cycle life, and … Read more
iNature Immunotherapy shows great promise in cancer treatment. However, the highly immunosuppressive nature of solid tumors limits its effectiveness. On October 15, 2024, the research paper titled “Zinc-Nickel Bimetallic Hydroxide Nanosheets Activate the Paraptosis–Pyroptosis Positive Feedback Cycle for Enhanced Tumor Immunotherapy” was published online in ACS Nano by Cheng Liang from Soochow University and Hou … Read more
iNature In clinical practice, capsules are widely used for oral administration of various drugs, but real-time tracking of drug release behavior and adjusting dosage based on therapeutic effects remains challenging. On December 11, 2024, Song Jibin from Beijing University of Chemical Technology and Mu Jing from Peking University co-authored a research paper titled “NIR-II Ratiometric … Read more
iNature Due to the non-invasive remote driving and drug loading capabilities of magnetic nanorobots, there are broad application prospects in thrombolytic therapy. Although nanorobots smaller than 100 nanometers are suitable for microvascular systems, their propulsion performance is severely affected due to limited response to magnetic fields. On October 18, 2024, Cheng Yu and He Bin … Read more
Shandong Provincial Medical Association of Ultrasound Submission Date: 2022-11-01 Corresponding Author: Li Jie, Email: [email protected]. Abstract:Nano-ultrasound contrast agents possess unique features such as liquid-gas phase transition and acoustic cavitation effects, making them important potential carriers for siRNA delivery. Currently, siRNA loading is mainly achieved through electrostatic attraction, requiring the construction of positively charged contrast agents … Read more