Unlocking Chemical Space: Electrochemically Driven Synthesis of Glycosyl Bicyclo[1.1.1]pentane Frameworks
Image source: J. Am. Chem. Soc.Introduction: In the past decade, [1.1.1]propellane derivatives (BCPs) have provided a unique three-dimensional spatial structure for drug chemistry as superior bioelectronic scaffolds. Meanwhile, glycosyl derivatives play a crucial role in chemical biology and drug discovery due to their widespread presence in bioactive molecules. However, the potential of [1.1.1]propellane as a … Read more