Year: 2025

Single-Dose Physically Cross-Linked Hyaluronic Acid and Lipid Hybrid Nanoparticles Activate Antitumor Immune Response

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Single-Dose Physically Cross-Linked Hyaluronic Acid and Lipid Hybrid Nanoparticles Activate Antitumor Immune Response

iNature Activating the STING pathway in the cytosol of tumor-infiltrating antigen-presenting cells (APCs) can trigger an effective antitumor immune response for cancer treatment. However, most STING agonists are hydrophilic small molecules that face rapid clearance and poor cytosolic delivery issues after systemic administration. Although various nanoparticles have been developed to facilitate cytosolic delivery, they often … Read more

Research Progress of Polyimide as Electrode Materials for Supercapacitors

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Research Progress of Polyimide as Electrode Materials for Supercapacitors

Research progress of polyimide as electrode materials for supercapacitors DING Chengcheng ,YU Juan ,HUANG Pei ,WANG Xiaodong （State Key Laboratory of Materials-Oriented Chemical Engineering，College of Chemical Engineering，Nanjing Tech University，Nanjing 211800，China） DOI：10.3969/j.issn.1001-3539.2024.01.025 Fund Information： National Natural Science Foundation Project (22035007) Abstract: The application advantages of supercapacitors and the development and characteristics of its electrode were briefly … Read more

Platinum(IV)-Backboned Polymer Prodrug-Functionalized Manganese Oxide Nanoparticles for Enhanced Lung Cancer Chemoimmunotherapy

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Platinum(IV)-Backboned Polymer Prodrug-Functionalized Manganese Oxide Nanoparticles for Enhanced Lung Cancer Chemoimmunotherapy

iNature The stimulator of interferon genes (STING) pathway shows great potential in reshaping the immunosuppressive tumor microenvironment and initiating anti-tumor immunity. However, effectively activating STING while avoiding toxic side effects from systemic administration remains challenging. On January 7, 2025, a communication from Li Weimin’s team at Sichuan University was published online in ACS Nano titled … Read more

Negligible Voltage Hysteresis With Strong Anionic Redox in Conventional Battery Electrode

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Negligible Voltage Hysteresis With Strong Anionic Redox in Conventional Battery Electrode

[Research Background] In traditional metal oxide cathode materials during charge and discharge processes, the insertion/extraction of alkali metal (lithium, sodium, potassium, etc.) ions requires charge compensation provided by transition metals, meaning that oxidation-reduction reactions occur as electrons are gained and lost. The number of electrons that can be transferred is one of the main limiting … Read more

Piezoelectric Vibration Sensor for Aircraft Engine Health Management

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Piezoelectric Vibration Sensor for Aircraft Engine Health Management

01 Overview Disadvantages of Existing Technology: The gear in the aircraft engine, as a key component for power transmission, can lead to fuel line issues and power interruptions if it fails, posing a serious risk to flight safety. Therefore, condition monitoring is particularly important. Current gear fault detection methods rely on vibration sensors, but aircraft … Read more

Monitoring Pyroptosis in B16 Cells Using Holographic 3D Imaging

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Monitoring Pyroptosis in B16 Cells Using Holographic 3D Imaging

Programmed cell death (PCD) plays a crucial role in triggering tumor cell death in the forefront of biomedical research. However, due to various drug resistance mechanisms in cancer, malignant tumor cells often develop resistance to commonly used apoptosis-inducing anticancer drugs. Considering that mitochondria are the sources of aerobic respiration and reactive oxygen species (ROS), we … Read more

Laser and Gold Nanoparticles: Breaking the Blood-Brain Barrier for Faster Drug Delivery

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Laser and Gold Nanoparticles: Breaking the Blood-Brain Barrier for Faster Drug Delivery

Written by | Xiao Xia Edited by | Wang Duoyu Formatted by | Shui Chengwen Blood-Brain Barrier (BBB) is the barrier formed between the plasma and brain cells by the walls of brain capillaries and glial cells, and the barrier formed between plasma and cerebrospinal fluid by the choroid plexus, only allowing specific types of … Read more

Ferumoxytol Nanoparticles Target Biofilms Causing Tooth Decay

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Ferumoxytol Nanoparticles Target Biofilms Causing Tooth Decay

Research Background Cavities (tooth decay) are an unresolved public health issue affecting over 2.3 billion people worldwide, particularly among the impoverished and those with poor medical conditions. Notably, iron deficiency anemia is closely related to severe cavities. Current preventive measures are insufficient for at-risk populations, especially in severe cases where high-sugar diets and poor oral … Read more

Super Sensitive Stretchable Strain Sensor Based on ZnO Nanoparticles Laser Induced Graphene

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Super Sensitive Stretchable Strain Sensor Based on ZnO Nanoparticles Laser Induced Graphene

↑ Click the “Graphene Alliance” above to follow us First Author: Do Hoon Lee Corresponding Author: Kuniharu Takei Affiliation: Hokkaido University DOI: 10.1021/acsnano.4c13156 Background Introduction Laser-induced graphene (LIG) adopts a bottom-up approach, directly converting carbon precursors into porous three-dimensional graphene through laser irradiation. As a macroscopic, low-cost conductive material, LIG has enormous potential for both … Read more

Enhanced Performance of TENG through Graphene Oxide and Transition Layer Coupling

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1Introduction to the Results The triboelectric nanogenerators (TENGs) have a simple structure, low manufacturing costs, and are suitable for harvesting low-frequency mechanical energy, thus providing a new method for green energy collection. Previous studies have mainly focused on the effects of single factors such as charge generation, storage, or loss on the electrical output of … Read more