Self-Assembly of Alkynyl Platinum(II) Complexes and Their Application in Sialic Acid Detection and Differentiation of Cancer Cells from Normal Cells

Self-Assembly of Alkynyl Platinum(II) Complexes and Their Application in Sialic Acid Detection and Differentiation of Cancer Cells from Normal Cells

In the field of life sciences, the sugar chains on the surface of cells act as complex “molecular codes” that carry critical biological information. Among them, sialic acid, a sugar molecule with a nine-carbon backbone, is typically located at the terminal of cell surface sugar chains and plays an important role in various biological processes … Read more

A New Strategy for Nanosuspension Stabilizer Screening Based on Computer-Aided Drug Design and Molecular Self-Assembly

A New Strategy for Nanosuspension Stabilizer Screening Based on Computer-Aided Drug Design and Molecular Self-Assembly

Nanosuspensions (NS) are considered dispersions of drug particles with a particle size of less than 1μm (most commonly 200-500nm) that are stabilized by adding suitable polymers and/or surfactants. By dispersing drugs into nanoscale particles, nanosuspensions significantly increase the specific surface area of the drug, thereby promoting drug dissolution and significantly improving its release performance and … Read more