Self-Assembly of Artificial Topological Nanostructures for Enhanced Bioorthogonal Activation and Drug Penetration in Cancer Immunotherapy
1. Research Background Despite significant efforts by scientists in developing cancer vaccines based on new antigens or mRNA, most research still focuses on the preventive stage. Eliciting substantial anti-tumor immune responses in patients remains a major challenge, primarily due to the weak immunogenicity of cancer vaccines, the immunosuppressive tumor microenvironment, and the low correlation between … Read more