👆Click the image to learn for free👆 What is the Insulin and C-Peptide Release Test? The insulin and C-peptide release test is a quantitative oral glucose (or steamed bun meal) test that raises blood sugar levels, stimulating the insulin β-cells to release insulin and C-peptide. By measuring the plasma insulin and C-peptide levels and their … Read more
Diabetes occurs due to dysfunction of pancreatic β cells and insufficient biological effects of insulin (insulin resistance), leading to increased blood sugar and decreased insulin levels. The changes in serum insulin/C-peptide concentrations measured at fasting and 30 minutes, 1 hour, 2 hours, and 3 hours after oral glucose during an Oral Glucose Tolerance Test (OGTT) … Read more
Diabetes patients, especially those diagnosed for the first time, often need to check their pancreatic function through blood tests. The main methods for checking pancreatic function are the insulin and C-peptide release tests, which are very important for diagnosing diabetes, determining its type and prognosis, and guiding treatment. In this issue, we will discuss how … Read more
C-peptide is a secretion product of pancreatic β-cells, and it shares a common precursor with insulin—proinsulin. One molecule of proinsulin, under specific conditions, splits into one molecule of insulin and one molecule of C-peptide; therefore, theoretically, C-peptide and insulin are secreted in equal amounts. The physiological functions of free C-peptide in the blood are not … Read more
2025 #Understanding C-Peptide Reports: From Values to Curves, Decoding the Secrets of Pancreatic Function!# 🔍 What is C-Peptide? Why measure it? C-Peptide (Connecting Peptide) is a “byproduct” of insulin secretion from pancreatic β-cells, produced in equal amounts to insulin. However, it is more stable than insulin—it is not metabolized by the liver and is not … Read more
C-peptide is widely used in daily clinical diagnosis and treatment. So why do we need to test C-peptide? How is C-peptide tested? How do we interpret the results? What is C-Peptide? Why Test for C-Peptide? C-peptide, also known as connecting peptide, is a secretion product of pancreatic β-cells. It shares a common precursor with insulin—proinsulin. … Read more
Common Patterns Insulin CPep Clinical Significance ↑↑ ↑↑ Insulinoma, insulin resistance (early stage of type 2 diabetes) ↑↑ ↓↓ Exogenous insulin use (artificial hypoglycemia) ↓↓ ↓↓ Type 1 diabetes, late stage type 2 diabetes Normal ↑↑ Insulin resistance (compensatory secretion increase) Assessment of Insulin Resistance Normal value: <2.5; >2.9 indicates insulin resistance. Interfering Factors and … Read more