Common Patterns
|
Insulin |
CPep |
Clinical Significance |
|
↑↑ |
↑↑ |
Insulinoma, insulin resistance (early stage of type 2 diabetes) |
|
↑↑ |
↓↓ |
Exogenous insulin use (artificial hypoglycemia) |
|
↓↓ |
↓↓ |
Type 1 diabetes, late stage type 2 diabetes |
|
Normal |
↑↑ |
Insulin resistance (compensatory secretion increase) |
Assessment of Insulin Resistance
Normal value: <2.5; >2.9 indicates insulin resistance.
Interfering Factors and PrecautionsTiming of testing: Fasting or postprandial state must be clearly indicated (postprandial C-peptide is more sensitive in reflecting β-cell reserve).Drug effects: Sulfonylureas stimulate endogenous insulin secretion → insulin ↑ + C-peptide ↑.Insulin injection → insulin ↑ + C-peptide ↓.Sample handling: Avoid hemolysis (affects insulin testing), store at low temperatures (C-peptide is more stable).This article is sourced from: Testing Starry Sky, the views expressed do not represent the platform’s views, and are for public welfare promotion of science, please contact for deletion if there is infringement!