AI protein design

EPFL Team Releases BindCraft AI System for Protein Binder Design with 10-100% Success Rate Without High-Throughput Screening

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EPFL Team Releases BindCraft AI System for Protein Binder Design with 10-100% Success Rate Without High-Throughput Screening

Exclusive compilation, unauthorized use will be pursued. Protein-protein interactions are at the core of all biological processes. Traditional protein binder design relies on methods such as immunization, antibody library screening, or directed evolution, which are often time-consuming and have a low success rate. Recently, the team led by Bruno E. Correia at the École Polytechnique … Read more

Nature | Open-source and Automated De Novo Protein Binder Design Process

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Nature | Open-source and Automated De Novo Protein Binder Design Process

Written by | Lin WuyuThe biological functions of proteins often depend on complex protein-protein interactions (PPIs), thus the ability to design specific protein binders that regulate these interactions holds great potential for therapeutic and biotechnological applications. Traditional methods such as immunization, antibody library screening, and directed evolution can produce binders, but they are often cumbersome, … Read more

BindCraft: A One-Shot Protein Design Tool for Functional Protein Binders (Nature 2025)

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BindCraft: A One-Shot Protein Design Tool for Functional Protein Binders (Nature 2025)

BindCraft is a new computational tool designed for the one-shot method of creating functional protein binders. https://www.nature.com/articles/s41586-025-09429-6 Here are some key points from the paper: [Apologies for the long delay in updates] What is BindCraft? BindCraft is an open-source, automated one-stop protein binder design process aimed at simplifying the de novo design of protein binders. … Read more

How Much Stress Do You Have? Check It Directly with Hormone Sensors

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How Much Stress Do You Have? Check It Directly with Hormone Sensors

Click the blue text to follow us Excess or deficiency of hormones in the body can lead to health hazards, including metabolic disorders and abnormal mental stress. Measuring hormone levels typically requires professional laboratory operations. Recently, Scitech Daily introduced a new type of artificial biosensor that can conveniently perform real-time hormone monitoring with more accurate … Read more